Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635097 | 0.98 | MAPT (0.65) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL9820267 | 0.84 | MAPT (0.61) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL30800484 | 0.84 | MAPT (0.61) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL6563884 | 0.84 | MAPT (0.61) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL4616467 | 0.83 | MAPT (0.59) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL11214950 | 0.81 | MAPT (0.57) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL8292078 | 0.80 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3662904 | 0.80 | MAPT (0.59) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL5157176 | 0.80 | MAPT (0.59) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 | |
| SCHEMBL9149907 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1RECQLHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1354882-A1 | DIPEPTIDYL PEPTIDASE IV INHIBITOR | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-10-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180925-A1 | Dipeptidylpeptidase-IV inhibitor | DPP4, DPP3, DPP9 | MAPT 3376/4885ALDH1A1 925/4885RECQL 4374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.