Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.35 |
| ▸ | MPI | P34949 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120559 | 0.72 | L3MBTL1 (0.48) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL7120554 | 0.70 | L3MBTL1 (0.41) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL11539280 | 0.70 | CTDSP1 (0.44) | SMN1; SMN2KMT2APMM2MPITDP1 | |
| SCHEMBL11209340 | 0.65 | MEN1 (0.34) | MEN1KMT2AALDH1A1 | |
| SCHEMBL2586772 | 0.65 | KMT2A (0.53) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| SCHEMBL2586777 | 0.65 | KMT2A (0.53) | MEN1KMT2AMAPTMAPK1ALDH1A1 | |
| Bromide SCHEMBL11212873 | 0.64 | MEN1 (0.33) | MEN1KMT2AALDH1A1 | |
| Bromide SCHEMBL11496054 | 0.64 | MEN1 (0.33) | MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11214486 | 0.64 | MEN1 (0.33) | MEN1KMT2AALDH1A1 | |
| SCHEMBL10669210 | 0.62 | PPARG (0.50) | HPGDSMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041246-B1 | 2-SUBSTITUTED-IMINO-3-ALKYL-TETRAHYDRO-6H-1,3,4-THIADIAZINE-5-ONES SALTS THEREOF AND THEIR PREPARATION | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1983-07-13 | — | — | EP | disclosed |
| EP-0018368-B1 | INSECTICIDAL 2-SUBSTITUTED-IMINO-3-ALKYL-5-DIALKOXYPHOSPHINOTHIOYLOXY-6H-1, 3,4-THIADIAZINES AND PREPARATION THEREOF | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1982-06-16 | — | — | EP | disclosed |
| EP-0041246-A2 | 2-Substituted-imino-3-alkyl-tetrahydro-6H-1,3,4-thiadiazine-5-ones salts thereof and their preparation | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1981-12-09 | — | — | EP | disclosed |
| EP-0018368-A1 | INSECTICIDAL 2-SUBSTITUTED-IMINO-3-ALKYL-5-DIALKOXYPHOSPHINOTHIOYLOXY-6H-1, 3,4-THIADIAZINES AND PREPARATION THEREOF. | CHEVRON RES (US) | 1980-11-12 | — | — | EP | disclosed |
| EP-0018368-A4 | INSECTICIDAL 2-SUBSTITUTED-IMINO-3-ALKYL-5-DIALKOXYPHOSPHINOTHIOYLOXY-6H-1, 3,4-THIADIAZINES AND PREPARATION THEREOF. | CHEVRON RES (US) | 1980-10-09 | — | — | EP | disclosed |
| WO-1979000829-A1 | INSECTICIDAL 2-SUBSTITUTED-IMINO-3-ALKYL-5-DIALKOXYPHOSPHINOTHIOLOXY-6H-1,3,4-THIADIAZINE,INTERMEDIATES THEREFOR AND PREPARATION THEREFOR | CHEVRON RES (US) | 1979-10-18 | — | — | WO | disclosed |
| US-4158732-A | Process for production of 2-substituted-imino-3-alkyl-tetrahydro-6H-1,3,4-thiadiazin-5-ones | CHEVRON RESEARCH COMPANY (US) | 1979-06-19 | — | — | US | disclosed |
| US-4144335-A | Insecticidal 2-substituted-imino-3-alkyl-5-dialkoxyphosphinothioyloxy-6H-1,3,4-thiadiazine | CHEVRON RESEARCH COMPANY (US) | 1979-03-13 | — | — | US | disclosed |