Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669207 | 1.00 | PPARG (0.50) | PPARGITGB3ITGAVMAPTMEN1 | |
| SCHEMBL10662770 | 0.83 | FAAH (0.54) | PPARGMAPTMEN1KMT2APLA2G1B | |
| SCHEMBL10662771 | 0.83 | FAAH (0.54) | PPARGMAPTMEN1KMT2APLA2G1B | |
| SCHEMBL10666251 | 0.82 | S1PR1 (0.48) | PPARGMAPTALDH1A1TDP1LMNA | |
| SCHEMBL10666243 | 0.82 | S1PR1 (0.48) | PPARGMAPTALDH1A1TDP1LMNA | |
| SCHEMBL10668341 | 0.72 | FAAH (0.44) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10668343 | 0.72 | FAAH (0.44) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL14883357 | 0.69 | ALDH1A1 (0.69) | ITGB3ITGAVMAPTMEN1KMT2A | |
| SCHEMBL10666221 | 0.69 | FAAH (0.52) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10666213 | 0.69 | FAAH (0.52) | MAPTMEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775677-A | ANTIALLERGNES, ANTIINFLAMMATORY AGENTS, CARDIOVASCULAR DISORDERS | WARNER-LAMBERT COMPANY (US) | 1988-10-04 | — | — | US | disclosed |