Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5588058 | 0.81 | SMN1; SMN2 (0.52) | TSHRSMN1; SMN2CYP2C19HIF1ACYP2C9 | |
| SCHEMBL10936836 | 0.79 | HSD17B10 (0.50) | HSD17B10HPGDSMN1; SMN2CYP2C19HIF1A | |
| SCHEMBL23542368 | 0.77 | HSD17B10 (0.39) | HSD17B10TSHRHPGDCASP1MAPK1 | |
| SCHEMBL24854238 | 0.75 | HSD17B10 (0.38) | HSD17B10TSHRHPGDCASP1MAPK1 | |
| SCHEMBL29575152 | 0.74 | HSD17B10 (0.46) | HSD17B10TSHRHPGDCASP1MAPK1 | |
| SCHEMBL10599641 | 0.73 | GAA (0.37) | HSD17B10TSHRHPGDCASP1MAPK1 | |
| SCHEMBL24945812 | 0.73 | ALDH1A1 (0.50) | HSD17B10TSHRHPGDCASP1MAPK1 | |
| SCHEMBL6230443 | 0.73 | CYP3A4 (0.41) | HSD17B10TSHRHPGDMAPK1SMN1; SMN2 | |
| SCHEMBL122888 | 0.73 | CA2 (0.38) | TSHRSMN1; SMN2CYP2C19CYP2C9CA2 | |
| SCHEMBL12251273 | 0.72 | ALDH1A1 (0.45) | HSD17B10TSHRHPGDCASP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4410736-A | Coupling of phenols with diphenoquinones | THE DOW CHEMICAL COMPANY (US) | 1983-10-18 | — | — | US | disclosed |