SCHEMBL112155

SCHEMBL112155

O=C1CN(CC(O)CO)C(=O)N1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.36
ATM Q13315 1/20 0.36
CRBN Q96SW2 1/20 0.34
PTGS1 P23219 2/20 0.34
TOP2A P11388 2/20 0.34
TOP2B Q02880 2/20 0.34
LMNA P02545 1/20 0.34
PER2 O15055 1/20 0.33
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PRF1 P14222 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31
CSNK2A1 P68400 1/20 0.31
CDK4 P11802 1/20 0.30
PRKACA P17612 1/20 0.30
PRKACG P22612 1/20 0.30
PRKACB P22694 1/20 0.30
CCND1 P24385 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11640405 0.90 PER2 (0.38) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL14422168 0.83 CRBN (0.38) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL9064412 0.82 CRBN (0.38) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL9190806 0.79 TOP2A (0.41) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL839300 0.74 TOP2A (0.46) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL9190564 0.72 CRBN (0.38) MAPTCRBNPTGS1TOP2ATOP2B
Formaldehyde SCHEMBL9059280 0.71 CRBN (0.39) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL2194813 0.71 CRBN (0.44) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL29071080 0.71 CRBN (0.40) MAPTCRBNPTGS1TOP2ATOP2B
SCHEMBL11598878 0.71 TOP2A (0.43) MAPTCRBNPTGS1TOP2ATOP2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12173178-B2 Polyfunctional hydrazide crosslinker PPG INDUSTRIES OHIO, INC. (US) 2024-12-24 US disclosed
US-20240117215-A1 POLYFUNCTIONAL HYDRAZIDE CROSSLINKER PPG INDUSTRIES OHIO, INC. (US) 2024-04-11 US disclosed
CN-116583547-A Multifunctional hydrazide crosslinking agents PPG工业俄亥俄公司 2023-08-11 CN disclosed
US-20230220219-A1 COMPOSITIONS CONTAINING THERMALLY CONDUCTIVE FILLERS PPG INDUSTRIES OHIO, INC. (US) 2023-07-13 US disclosed
US-20230120549-A1 Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same PPG INDUSTRIES OHIO, INC. 2023-04-20 US disclosed
US-11591436-B2 Polyurethane article and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2023-02-28 US disclosed
CN-115702189-A Composition containing thermally conductive filler PPG工业俄亥俄公司 2023-02-14 CN disclosed
US-11472912-B2 Polyurethanes, articles and coatings prepared therefrom and methods of making the same PPG INDUSTRIES OHIO, INC. (US) 2022-10-18 US disclosed
US-20220119581-A1 Aircraft Windows PPG INDUSTRIES, INC. 2022-04-21 US disclosed
US-20220112328-A1 \"Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same\ PPG INDUSTRIES OHIO, INC. 2022-04-14 US disclosed
EP-1149138-A1 POLYANHYDRIDE PHOTOCHROMIC COATING COMPOSITION AND PHOTOCHROMIC ARTICLES PPG Industries Ohio, Inc. (US) 2001-10-31 EP disclosed
US-6268055-B1 CURED OVERCOATING PPG INDUSTRIES OHIO, INC. 2001-07-31 US disclosed
US-6187444-B1 Photochromic polyurethane coating and articles having such a coating PPG INDUSTRIES OHIO, INC. 2001-02-13 US disclosed
EP-1037951-A1 PHOTOCHROMIC EPOXY RESIN COATING COMPOSITION PPG Industries Ohio, Inc. (US) 2000-09-27 EP disclosed
WO-2000036049-A1 AMINOPLAST RESIN PHOTOCHROMIC COATING COMPOSITION AND PHOTOCHROMIC ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2000-06-22 WO disclosed
WO-2000036048-A1 AMINOPLAST RESIN PHOTOCHROMIC COATING COMPOSITION AND PHOTOCHROMIC ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2000-06-22 WO disclosed
WO-2000034410-A1 POLYANHYDRIDE PHOTOCHROMIC COATING COMPOSITON AND PHOTOCHROMIC ARTICLES PPG INDUSTRIES OHIO, INC. (US) 2000-06-15 WO disclosed
EP-0963390-A1 PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING PPG Industries Ohio, Inc. (US) 1999-12-15 EP disclosed
WO-1999029791-A1 PHOTOCHROMIC EPOXY RESIN COATING COMPOSITION PPG INDUSTRIES OHIO, INC. (US) 1999-06-17 WO disclosed
WO-1998037115-A1 PHOTOCHROMIC POLYURETHANE COATING AND ARTICLES HAVING SUCH A COATING PPG INDUSTRIES OHIO, INC. (US) 1998-08-27 WO disclosed