Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476921 | 0.84 | SMN1; SMN2 (0.37) | TSHRACHESMN1; SMN2 | |
| SCHEMBL28259670 | 0.80 | MME (0.39) | ACHESMN1; SMN2 | |
| SCHEMBL5141898 | 0.79 | GAA (0.47) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL8808086 | 0.79 | ACHE (0.34) | MGAMGAASIMGAM2ACHE | |
| SCHEMBL5143585 | 0.73 | MME (0.47) | MGAMGAASIMGAM2TSHR | |
| SCHEMBL7854706 | 0.71 | CA1 (0.42) | TSHRACHESMN1; SMN2 | |
| SCHEMBL17885840 | 0.70 | — | — | |
| SCHEMBL6049901 | 0.70 | — | — | |
| SCHEMBL10129641 | 0.70 | — | — | |
| SCHEMBL18344486 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0022482-B1 | PROCESS FOR PREPARING 4-HYDROXY-3-METHYL-2-(2-PROPYNYL)-2-CYCLOPENTENOLONE; A GAMMA-DIKETONE COMPOUND AND SUBSTITUTED ACETONEDICARBOXYLIC ESTERS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-09-14 | — | — | EP | disclosed |
| US-4343953-A | STARTING WITH A 3-OXO-GLUTARATE AND 3-CHLOROPROPYNE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-08-10 | — | — | US | disclosed |
| EP-0022482-A2 | Process for preparing 4-hydroxy-3-methyl-2-(2-propynyl)-2-cyclopentenolone; a gamma-diketone compound and substituted acetonedicarboxylic esters | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-01-21 | — | — | EP | disclosed |