Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476921 | 0.89 | SMN1; SMN2 (0.37) | ACHESMN1; SMN2MMECA1CA2 | |
| SCHEMBL28259670 | 0.85 | MME (0.39) | ACHESMN1; SMN2MMECA1CA2 | |
| SCHEMBL9186422 | 0.83 | MME (0.36) | SMN1; SMN2MMEALDH1A1CA1CA2 | |
| SCHEMBL435187 | 0.82 | GRIK1 (0.35) | — | |
| SCHEMBL9023602 | 0.82 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1MGAMGAASI | |
| SCHEMBL11215591 | 0.79 | MGAM (0.35) | ACHESMN1; SMN2MGAMGAASI | |
| SCHEMBL25575102 | 0.78 | GRIK1 (0.42) | — | |
| SCHEMBL12818602 | 0.77 | USP2 (0.42) | ACHEALDH1A1CA1CA2 | |
| SCHEMBL7854706 | 0.76 | CA1 (0.42) | ACHESMN1; SMN2MMECA1CA2 | |
| SCHEMBL13751258 | 0.75 | SMN1; SMN2 (0.40) | SMN1; SMN2MMEALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0257102-B1 | AGENTS FOR TREATING NEUROPHATHY | MITSUI PETROCHEMICAL IND (JP) | 1997-11-19 | — | — | EP | disclosed |
| EP-0799617-A2 | Therapeutic agent for neurological diseases | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-4959368-A | PYRIMIDINE DERIVATIVES | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1990-09-25 | — | — | US | disclosed |
| EP-0257102-A1 | AGENTS FOR TREATING NEUROPHATHY | Mitsui Chemicals, Inc. (JP) | 1988-03-02 | — | — | EP | disclosed |