SCHEMBL11215754

SCHEMBL11215754

O=C(O)C1CCc2ccccc21.[Zn]

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PIN1 Q13526 5/20 0.58
TSHR P16473 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
KCNQ2 O43526 1/20 0.47
CYP11B2 P19099 1/20 0.44
HTT P42858 1/20 0.44
IDO1 P14902 1/20 0.43
PDPK1 O15530 1/20 0.43
CRBN Q96SW2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL907688 0.98 PIN1 (0.60) PIN1TSHRNPSR1KCNQ2CYP11B2
SCHEMBL2790690 0.98 PIN1 (0.60) PIN1TSHRNPSR1KCNQ2CYP11B2
SCHEMBL1400973 0.98 PIN1 (0.60) PIN1TSHRNPSR1KCNQ2CYP11B2
SCHEMBL12431131 0.98 PIN1 (0.60) PIN1TSHRNPSR1KCNQ2CYP11B2
Hydrochloric Acid SCHEMBL7213722 0.96 PIN1 (0.58) PIN1TSHRNPSR1KCNQ2CYP11B2
SCHEMBL2792830 0.87 HTT (0.54) PIN1TSHRNPSR1HTT
SCHEMBL242244 0.87 HTT (0.54) PIN1TSHRNPSR1HTT
SCHEMBL29608780 0.87 HTT (0.54) PIN1TSHRNPSR1HTT
SCHEMBL29706163 0.87 HTT (0.54) PIN1TSHRNPSR1HTT
SCHEMBL2796237 0.87 HTT (0.54) PIN1TSHRNPSR1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57156434-A None JP disclosed
JP-S57156434-A ZINC INDANECARBOXYLATE TAKEDA CHEM IND LTD 1982-09-27 JP disclosed