Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 5/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12431131 | 1.00 | PIN1 (0.60) | PIN1TSHRNPSR1KCNQ2CYP11B2 | |
| SCHEMBL1400973 | 1.00 | PIN1 (0.60) | PIN1TSHRNPSR1KCNQ2CYP11B2 | |
| SCHEMBL907688 | 1.00 | PIN1 (0.60) | PIN1TSHRNPSR1KCNQ2CYP11B2 | |
| Hydrochloric Acid SCHEMBL7213722 | 0.98 | PIN1 (0.58) | PIN1TSHRNPSR1KCNQ2CYP11B2 | |
| SCHEMBL11215754 | 0.98 | PIN1 (0.58) | PIN1TSHRNPSR1KCNQ2CYP11B2 | |
| SCHEMBL2792830 | 0.89 | HTT (0.54) | PIN1TSHRNPSR1HTT | |
| SCHEMBL2796237 | 0.89 | HTT (0.54) | PIN1TSHRNPSR1HTT | |
| SCHEMBL29608780 | 0.89 | HTT (0.54) | PIN1TSHRNPSR1HTT | |
| SCHEMBL29706163 | 0.89 | HTT (0.54) | PIN1TSHRNPSR1HTT | |
| SCHEMBL242244 | 0.89 | HTT (0.54) | PIN1TSHRNPSR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174492-A1 | SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20230174492-A1 | SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20230174492-A1 | SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS | ELANCO ANIMAL HEALTH GMBH (DE) | 2023-06-08 | — | — | US | disclosed |
| US-20100168102-A9 | Amide Derivatives as Kinase Inhibitors | DEVGEN NV (BE) | 2010-07-01 | — | — | US | disclosed |
| US-20090118283-A1 | Amide Derivatives as Kinase Inhibitors | DEVGEN NV (BE) | 2009-05-07 | — | — | US | disclosed |
| CN-101296904-A | Amide derivatives as kinase inhibitors | DEVGEN NV (BE) | 2008-10-29 | — | — | CN | disclosed |
| EP-1907361-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | Devgen N.V. (BE) | 2008-04-09 | — | — | EP | disclosed |
| US-20070105916-A1 | Amphiphilic pyridinium compounds, method of making and use thereof | THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC. | 2007-05-10 | — | — | US | disclosed |
| WO-2007006546-A1 | AMIDE DERIVATIVES AS KINASE INHIBITORS | DEVGEN N.V. (BE) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168102-A9 | Amide Derivatives as Kinase Inhibitors | MAP3K1, CDK1, CDK2 | PIN1 1717/4885TSHR 1684/4885NPSR1 886/4885 |
| US-20070105916-A1 | Amphiphilic pyridinium compounds, method of making and use thereof | CXCL8, IL18, CCR8 | PIN1 472/4885TSHR 3290/4885NPSR1 2474/4885 |
| US-20090118283-A1 | Amide Derivatives as Kinase Inhibitors | MAP3K1, CDK1, CDK2 | PIN1 1717/4885TSHR 1684/4885NPSR1 886/4885 |
| US-20230174492-A1 | SUBSTITUTED CONDENSED AZINES AS ANTHELMINTIC COMPOUNDS | H1-5, H1-10, H1-0 | PIN1 3838/4885TSHR 1894/4885NPSR1 2710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.