Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.57 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.57 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.57 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | ALB | P02768 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28245503 | 0.91 | PTGS2 (0.67) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL28864894 | 0.91 | PTGS2 (0.67) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL1067026 | 0.91 | PTGS2 (0.67) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| Hydrochloric Acid SCHEMBL1178592 | 0.90 | PTGS2 (0.65) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL11135627 | 0.85 | PTGS2 (0.59) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| Benzylamine SCHEMBL28122435 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| Benzylamine SCHEMBL28122433 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7704968 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL5313395 | 0.80 | PTGS2 (0.71) | PTGS2PTGS1CXCR1CXCR2LMNA | |
| SCHEMBL7150384 | 0.80 | HDAC3 (0.61) | LMNAESR1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57136553-A | — | — | None | — | — | JP | disclosed |
| JP-S57136553-A | AMINOCARBOXYLIC ACID DERIVATIVE, ITS PREPARATION AND ANTIULCER AGENT CONTAINING THE SAME AS ACTIVE CONSTITUENT | TEIJIN LTD | 1982-08-23 | — | — | JP | disclosed |