SCHEMBL7150384

SCHEMBL7150384

NCc1ccc(C(=O)c2ccc(CN)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 1/20 0.61
HDAC6 Q9UBN7 1/20 0.61
NCOR2 Q9Y618 1/20 0.61
LOXL2 Q9Y4K0 4/20 0.59
F10 P00742 1/20 0.56
ABAT P80404 1/20 0.52
TPSAB1 Q15661 3/20 0.50
HRH3 Q9Y5N1 1/20 0.50
LMNA P02545 2/20 0.48
SRD5A2 P31213 2/20 0.48
ESR1 P03372 1/20 0.48
ESR2 Q92731 1/20 0.48
MAPT P10636 1/20 0.48
PKM P14618 1/20 0.48
HPGD P15428 1/20 0.48
HTT P42858 1/20 0.48
NOS3 P29474 2/20 0.46
NOS1 P29475 2/20 0.46
NOS2 P35228 2/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8833446 0.97 HDAC3 (0.59) HDAC3HDAC6NCOR2LOXL2F10
SCHEMBL203283 0.91 ALDH1A1 (0.61) HDAC3HDAC6NCOR2LOXL2LMNA
Hydrochloric Acid SCHEMBL2450035 0.89 ALDH1A1 (0.58) HDAC3HDAC6NCOR2LOXL2LMNA
SCHEMBL11136679 0.87 HDAC3 (0.50) HDAC3HDAC6NCOR2LOXL2F10
SCHEMBL27665172 0.87 LOXL2 (0.58) HDAC3HDAC6NCOR2LOXL2F10
SCHEMBL11137347 0.87 CA2 (0.55) HDAC3HDAC6NCOR2LOXL2F10
SCHEMBL11135171 0.87 SRD5A2 (0.59) HDAC3HDAC6NCOR2LOXL2F10
Hydrochloric Acid SCHEMBL11134658 0.85 SRD5A2 (0.57) HDAC3HDAC6NCOR2LOXL2F10
SCHEMBL11132309 0.84 SRD5A2 (0.61) HDAC3HDAC6NCOR2LOXL2SRD5A2
SCHEMBL11136383 0.84 HDAC3 (0.47) HDAC3HDAC6NCOR2LOXL2F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114089599-A Metal nanoparticle-based photoresist composition and application thereof 中国科学院理化技术研究所 2022-02-25 CN claimed
CN-110437136-A 1- virtue oxygen ethyl piperidine -4- base methanone derivatives and its preparation method and application UNIV SOUTHEAST 2019-11-12 CN claimed
CN-108947924-A The preparation method and its usage of dihydro-isoxazole methanone derivatives and dihydro-isoxazole methanone derivatives 石河子大学 2018-12-07 CN claimed
CN-108947997-A The copper catalysis series connection cyclization that a kind of oxygen participates in constructs N-5- carbonyl thiazole indoles 山东博苑医药化学有限公司 2018-12-07 CN claimed
CN-102341379-B Benzothiazine derivative, its preparation method and the application as medicine thereof PIERRE FABRE MEDICAMENT (FR) 2015-08-26 CN claimed
CN-104093709-A Imidazolylketone derivatives as aldosterone synthase inhibitors HOFFMANN LA ROCHE 2014-10-08 CN claimed
CN-104016898-A 3,4-disubstituted pyrrole compound as well as preparation method and application thereof UNIV SHANGHAI JIAOTONG 2014-09-03 CN claimed
CN-102341379-A Derivatives of benzothiazines, preparation thereof and application thereof as drugs PF MEDICAMENT 2012-02-01 CN claimed
CN-101484163-A 2-Benzoyl-imidazopyridine derivatives, their preparation and their therapeutic use SANOFI AVENTIS (FR) 2009-07-15 CN claimed
CN-114089599-A Metal nanoparticle-based photoresist composition and application thereof 中国科学院理化技术研究所 2022-02-25 CN disclosed
CN-110437136-A 1- virtue oxygen ethyl piperidine -4- base methanone derivatives and its preparation method and application UNIV SOUTHEAST 2019-11-12 CN disclosed
CN-109627152-A A kind of photocatalytic synthesis method of cyclohexyl-(4-R phenyl) first ketone compounds and its application 甘肃金盾化工有限责任公司 2019-04-16 CN disclosed
CN-109369406-A A kind of photocatalytic synthesis method of 1- hydroxycyclohexyl phenyl ketone class compound and its application 甘肃金盾化工有限责任公司 2019-02-22 CN disclosed
CN-108947924-A The preparation method and its usage of dihydro-isoxazole methanone derivatives and dihydro-isoxazole methanone derivatives 石河子大学 2018-12-07 CN disclosed
EP-1129146-A1 AQUEOUS COATING COMPOSITION COMPRISING A MIXTURE OF POLYURETHANE DISPERSIONS Akzo Nobel N.V. (NL) 2001-09-05 EP disclosed
WO-2000024837-A1 AQUEOUS COATING COMPOSITION COMPRISING A MIXTURE OF POLYURETHANE DISPERSIONS AKZO NOBEL N.V. (NL) 2000-05-04 WO disclosed
US-5192654-A Piperidine stabilizer, cyanine or merocyanine sensitizer, speed, storage sability FUJI PHOTO FILM CO., LTD. (JP) 1993-03-09 US disclosed
EP-0332326-B1 POLYURETHANE COATING COMPOSITIONS ICI RESINS BV (NL) 1993-03-03 EP disclosed
US-4983662-A SELF-CROSSLINKING THROUGH HYDRAZINE OR HYDRAZONE AND CARBONYL FUNCTIONAL GROUPS ICI RESINS B.V. (NL) 1991-01-08 US disclosed
EP-0332326-A2 Polyurethane coating compositions ICI RESINS BV (NL) 1989-09-13 EP disclosed