Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.51 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | BACE1 | P56817 | 7/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373877 | 0.83 | GRIN2B (0.50) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL5347556 | 0.79 | GRIN2B (0.62) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL2092320 | 0.76 | GRIN2B (0.54) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL663239 | 0.76 | GRIN2B (0.74) | GRIN2BACHEBACE1BCHEMEN1 | |
| Hydrochloric Acid SCHEMBL2550113 | 0.74 | MEN1 (0.78) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL73496 | 0.74 | CARM1 (0.37) | MEN1KMT2ARAB9ACARM1PRMT6 | |
| SCHEMBL4173336 | 0.72 | GRIN2B (0.69) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL2954218 | 0.72 | GRIN2B (0.69) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL433970 | 0.72 | GRIN2B (0.69) | GRIN2BACHEBACE1BCHEMEN1 | |
| SCHEMBL24574127 | 0.71 | HRH3 (0.71) | GRIN2BACHEBACE1BCHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0004358-B1 | N-OXACYCLYLALKYL PIPERIDINES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | CIBA-GEIGY AG (CH) | 1982-01-06 | — | — | EP | disclosed |
| EP-0004358-A1 | N-oxacyclylalkyl piperidines, process for their preparation, pharmaceutical compositions containing these compounds | CIBA-GEIGY AG (CH) | 1979-10-03 | — | — | EP | disclosed |