Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 3/20 | 0.62 |
| ▸ | ACHE | P22303 | 3/20 | 0.62 |
| ▸ | BACE1 | P56817 | 3/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | FABP6 | P51161 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2954218 | 1.00 | GRIN2B (0.69) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| Bromide SCHEMBL11703466 | 0.98 | GRIN2B (0.67) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| Hydrochloric Acid SCHEMBL30509625 | 0.98 | GRIN2B (0.67) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL433970 | 0.96 | GRIN2B (0.69) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL24574127 | 0.94 | HRH3 (0.71) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL1847296 | 0.94 | HRH3 (0.71) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| Hydrochloric Acid SCHEMBL11785266 | 0.94 | GRIN2B (0.67) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL10789534 | 0.94 | HRH3 (0.71) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL294763 | 0.94 | HRH3 (0.71) | GRIN2BMEN1KMT2ARAB9ABCHE | |
| SCHEMBL13280563 | 0.92 | GRIN2B (0.59) | GRIN2BMEN1KMT2ARAB9ABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | AMGEN INC. (US) | 2009-09-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090227601-A1 | Bradykinin 1 Receptor Antagonists | BDKRB1, BDKRB2, VIPR1 | GRIN2B 471/4885MEN1 662/4885KMT2A 3358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.