Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.69 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | BCHE | P06276 | 2/20 | 0.62 |
| ▸ | ACHE | P22303 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | FABP6 | P51161 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.56 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11785266 | 0.98 | GRIN2B (0.67) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL10789534 | 0.98 | HRH3 (0.71) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL294763 | 0.98 | HRH3 (0.71) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL1847296 | 0.98 | HRH3 (0.71) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL24574127 | 0.98 | HRH3 (0.71) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11782513 | 0.96 | HRH3 (0.69) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL11781778 | 0.96 | HRH3 (0.69) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL2954218 | 0.96 | GRIN2B (0.69) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| SCHEMBL4173336 | 0.96 | GRIN2B (0.69) | GRIN2BHRH3MEN1RAB9AKMT2A | |
| Bromide SCHEMBL18131548 | 0.94 | HRH3 (0.67) | GRIN2BHRH3MEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2513227-A2 | CATALYSTS FOR POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | Honeywell International Inc. (US) | 2012-10-24 | — | — | EP | claimed |
| WO-2011084563-A2 | CATALYSTS FOR POLYURETHANE FOAM POLYOL PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS | HONEYWELL INTERNATIONAL INC. (US) | 2011-07-14 | — | — | WO | claimed |
| EP-4705291-A1 | IKK-ALPHA INHIBITORS | Cancer Research Technology Limited (GB) | 2026-03-11 | — | — | EP | disclosed |
| EP-3938340-B1 | HETEROAROMATIC AND HETEROBICYCLIC AROMATIC DERIVATIVES FOR THE TREATMENT OF FERROPTOSIS-RELATED DISORDERS | COLLABORATIVE MEDICINAL DEV LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024263563-A1 | METABOTROPIC GLUTAMATE SUBTYPE-2 AND -3 RECEPTOR POSITIVE ALLOSTERIC MODULATORS AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-12-26 | — | — | WO | disclosed |
| WO-2024228035-A1 | IKK-ALPHA INHIBITORS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2024-11-07 | — | — | WO | disclosed |
| US-20240051974-A1 | DIRECT REDUCTIVE AMINATIONS WITH MONOTRIFLUOROACETOXY BORANE-AMINES | PURDUE RESEARCH FOUNDATION (US) | 2024-02-15 | — | — | US | disclosed |
| US-11697634-B2 | Method and mixture to form functionalized cyclic compounds | NATIONAL TSING HUA UNIVERSITY (TW) | 2023-07-11 | — | — | US | disclosed |
| US-20230172940-A1 | METHODS OF EXTENDING LIFESPAN BY ADMINISTERING FERROPTOSIS INHIBITORS | COLLABORATIVE MEDICINAL DEVELOPMENT, LLC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230172940-A1 | METHODS OF EXTENDING LIFESPAN BY ADMINISTERING FERROPTOSIS INHIBITORS | COLLABORATIVE MEDICINAL DEVELOPMENT, LLC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20220144826-A1 | Heteroaromatic and Heterobicyclic Aromatic Derivatives for the Treatment of Ferroptosis-Related Disorders | COLLABORATIVE MEDICINAL DEVELOPMENT, LLC (US) | 2022-05-12 | — | — | US | disclosed |
| CN-1871012-A | 7 and 8 membered heterocyclic cyclopentyl benzylamide modulators of chemokine receptor activity | MERCK & CO INC (US) | 2006-11-29 | — | — | CN | disclosed |
| US-20060183731-A1 | 7 and 8 membered heterocyclic cyclopentyl benzylamide modulators of chemokine receptor activity | MERCK & CO., INC. | 2006-08-17 | — | — | US | disclosed |
| CN-1247553-C | 2-imino-1,3-thiazine derivs. | SHIONOGI & CO (JP) | 2006-03-29 | — | — | CN | disclosed |
| WO-2005111002-A2 | SUBSTITUTED CYCLOALKYL DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY DISEASES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |
| CN-1514831-A | Medicinal composition containing 1,3-thiazine derivative | ��Ұ����ҩ��ʽ���� | 2004-07-21 | — | — | CN | disclosed |
| CN-1387519-A | 2-imino-1, 3-thiazine derivatives | SHIONOGI & CO (JP) | 2002-12-25 | — | — | CN | disclosed |
| US-4048229-A | ANTAGONIST ACTIVITY | SMITHKLINE CORPORATION (US) | 1977-09-13 | — | — | US | disclosed |
| US-3976694-A | BETA-ADRENERGIC STIMULANT, BRONCHODILATOR | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | disclosed |
| US-3961076-A | BRONCHODILATORS | SMITHKLINE CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11697634-B2 | Method and mixture to form functionalized cyclic compounds | BDKRB2, BDKRB1, CYP11B2 | GRIN2B 48/4885HRH3 29/4885MEN1 284/4885 |
| US-20230172940-A1 | METHODS OF EXTENDING LIFESPAN BY ADMINISTERING FERROPTOSIS INHIBITORS | GPX4, GPX1, AIFM2 | GRIN2B 3690/4885HRH3 4653/4885MEN1 2820/4885 |
| US-20220144826-A1 | Heteroaromatic and Heterobicyclic Aromatic Derivatives for the Treatment of Ferroptosis-Related Disorders | AIFM2, FECH, SLC40A1 | GRIN2B 1187/4885HRH3 303/4885MEN1 2006/4885 |
| US-20240051974-A1 | DIRECT REDUCTIVE AMINATIONS WITH MONOTRIFLUOROACETOXY BORANE-AMINES | MAOB, BCAT2, AADAT | GRIN2B 361/4885HRH3 766/4885MEN1 1199/4885 |
| US-20060183731-A1 | 7 and 8 membered heterocyclic cyclopentyl benzylamide modulators of chemokine receptor activity | CCR2, CCR6, CCR9 | GRIN2B 2306/4885HRH3 112/4885MEN1 4173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.