Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11215914 | 0.86 | PTGS1 (0.49) | PTGS1RXRARXRBALOX5ALDH1A1 | |
| SCHEMBL2400875 | 0.85 | L3MBTL1 (0.59) | PTGS1L3MBTL1TRPM8 | |
| SCHEMBL11214528 | 0.82 | PARP10 (0.46) | PTGS1RXRARXRBALOX5PARP10 | |
| SCHEMBL1416702 | 0.81 | PTGS1 (0.73) | PTGS1RXRARXRBALDH1A1ACHE | |
| SCHEMBL11519182 | 0.81 | RXRA (0.40) | PTGS1RXRARXRBALOX5PARP10 | |
| SCHEMBL6396086 | 0.80 | PTGS1 (0.53) | PTGS1RXRARXRBALOX5ALDH1A1 | |
| SCHEMBL6402645 | 0.80 | PTGS1 (0.53) | PTGS1RXRARXRBALOX5ALDH1A1 | |
| SCHEMBL6396089 | 0.80 | PTGS1 (0.53) | PTGS1RXRARXRBALOX5ALDH1A1 | |
| SCHEMBL5746015 | 0.79 | PTGS1 (0.51) | PTGS1RXRARXRBALOX5ALDH1A1 | |
| SCHEMBL8589033 | 0.79 | PTGS1 (0.51) | PTGS1RXRARXRBALOX5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |