SCHEMBL11215980

SCHEMBL11215980

CCO[Si](CCCNC(=O)NCCCl)(OCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 6/20 0.41
FAAH O00519 3/20 0.39
KDM4E B2RXH2 1/20 0.34
LMNA P02545 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
PRMT1 Q99873 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
CNR1 P21554 1/20 0.32
CNR2 P34972 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
EPHX2 P34913 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561394 0.91 EPHX1 (0.48) EPHX1TSHRCA12CA1CA2
SCHEMBL4419366 0.89 EPHX1 (0.47) EPHX1TSHRCA12CA1CA2
SCHEMBL4362272 0.87 EPHX1 (0.55) EPHX1KDM4ECA12CA1CA2
SCHEMBL4355762 0.86 EPHX1 (0.57) EPHX1EPHX2
SCHEMBL28435450 0.86 EPHX1 (0.55) EPHX1KDM4EALDH1A1EPHX2
SCHEMBL21360055 0.86 EPHX1 (0.44) EPHX1TSHRCA12CA1CA2
SCHEMBL19838195 0.85 EPHX1 (0.52) EPHX1KDM4ECA12CA1CA2
SCHEMBL4355837 0.84 EPHX1 (0.42) EPHX1LMNATSHRCA12CA1
SCHEMBL12761200 0.83 EPHX1 (0.63) EPHX1EPHX2
SCHEMBL21360054 0.83 EPHX1 (0.56) EPHX1EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57105423-A None JP disclosed
JP-S57105423-A CHLOROETHYLUREIDOPROPYLPOLYSILSESQUIOXANE TOKUYAMA SODA CO LTD 1982-06-30 JP disclosed