SCHEMBL4355837

SCHEMBL4355837

CCO[Si](CCCNC(=O)NCCC[Si](OC)(OC)OC)(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 8/20 0.42
TSHR P16473 1/20 0.36
EPHX2 P34913 1/20 0.36
PRMT1 Q99873 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
LMNA P02545 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2561394 0.93 EPHX1 (0.48) EPHX1TSHREPHX2PRMT1CA12
SCHEMBL4419366 0.91 EPHX1 (0.47) EPHX1TSHREPHX2PRMT1CA12
SCHEMBL4362272 0.89 EPHX1 (0.55) EPHX1EPHX2PRMT1CA12CA1
SCHEMBL254189 0.89 EPHX1 (0.46) EPHX1TSHREPHX2PRMT1MEN1
SCHEMBL28435450 0.87 EPHX1 (0.55) EPHX1EPHX2MEN1KMT2ASMN1; SMN2
SCHEMBL21360055 0.87 EPHX1 (0.44) EPHX1TSHREPHX2PRMT1CA12
SCHEMBL4355762 0.87 EPHX1 (0.57) EPHX1EPHX2
SCHEMBL19838195 0.87 EPHX1 (0.52) EPHX1EPHX2PRMT1CA12CA1
SCHEMBL9985974 0.86 EPHX1 (0.33) EPHX1TSHRCA12CA1CA2
SCHEMBL10557593 0.85 EPHX1 (0.57) EPHX1EPHX2LMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
EP-2138501-B1 Functional silane compound, coating solution, and method for manufacturing plastic lens HOYA CORP (JP) 2014-08-13 EP disclosed
EP-2138501-A2 Functional silane compound, coating solution, and method for manufacturing plastic lens Hoya Corporation (JP) 2009-12-30 EP disclosed
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS HOYA CORPORATION (JP) 2009-12-24 US disclosed
EP-0216868-A1 AN AUTO-ADHERING ONE-COMPONENT RTV SILICONE SEALANT COMPOSITION UTILIZING AN ADHESION PROMOTER LOCTITE CORPORATION (US) 1987-04-08 EP disclosed
WO-1986005798-A1 AN AUTO-ADHERING ONE-COMPONENT RTV SILICONE SEALANT COMPOSITION UTILIZING AN ADHESION PROMOTER LOCTITE CORPORATION (US) 1986-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090317541-A1 FUNCTIONAL SILANE COMPOUND, COATING SOLUTION, AND METHOD FOR MANUFACTURING PLASTIC LENS SUMO1, CAD, UFM1 EPHX1 4148/4885TSHR 4052/4885EPHX2 3798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.