Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 6/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.45 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10506137 | 0.87 | MEN1 (0.58) | MEN1KMT2APOLBBLMTDP1 | |
| SCHEMBL8138470 | 0.85 | MAOB (0.50) | MEN1KMT2APOLBBLMTDP1 | |
| SCHEMBL3371954 | 0.84 | MEN1 (0.51) | MEN1KMT2APOLBBLMTDP1 | |
| SCHEMBL1249954 | 0.84 | ALOX15 (0.61) | MEN1KMT2AMAPTMAOBTBXAS1 | |
| SCHEMBL11216005 | 0.82 | MAOB (0.46) | MAOBPARP10KEAP1NFE2L2ST14 | |
| SCHEMBL1480561 | 0.82 | RXRA (0.53) | KMT2ARAB9AMAPT | |
| Hydrochloric Acid SCHEMBL3605426 | 0.82 | ALOX15 (0.59) | MEN1KMT2AMAPTMAOBTBXAS1 | |
| SCHEMBL14546296 | 0.82 | MEN1 (0.47) | MEN1KMT2APOLBBLMTDP1 | |
| SCHEMBL2798360 | 0.82 | MEN1 (0.47) | MEN1KMT2APOLBBLMTDP1 | |
| SCHEMBL23582938 | 0.81 | PLA2G4B (0.55) | MEN1KMT2ARAB9ATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |