Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9323457 | 0.84 | APP (0.41) | GBA1APPNLRP3EPHX2 | |
| SCHEMBL142227 | 0.84 | APP (0.41) | GBA1APPNLRP3EPHX2 | |
| SCHEMBL3309834 | 0.83 | APP (0.44) | GBA1APPNLRP3EPHX2 | |
| SCHEMBL3312499 | 0.81 | APP (0.42) | GBA1APPNLRP3 | |
| SCHEMBL3310664 | 0.81 | APP (0.42) | GBA1APPNLRP3 | |
| SCHEMBL9322595 | 0.81 | — | — | |
| SCHEMBL3457117 | 0.81 | GBA1 (0.41) | GBA1 | |
| SCHEMBL918312 | 0.81 | APP (0.50) | APPRELAEPHX2 | |
| SCHEMBL13016325 | 0.81 | GBA1 (0.41) | GBA1 | |
| SCHEMBL28774460 | 0.79 | APP (0.44) | APPNLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322535-A | REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE | FMC CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |