SCHEMBL918312

SCHEMBL918312

O=S(=O)(O)CCCNCCCS(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.50
CYP2C19 P33261 3/20 0.41
PTGS1 P23219 1/20 0.41
PDE4A P27815 1/20 0.41
LMNA P02545 1/20 0.41
SLC6A6 P31641 1/20 0.41
BLM P54132 1/20 0.41
CA2 P00918 5/20 0.36
CYP1A2 P05177 3/20 0.36
CA12 O43570 3/20 0.36
CA4 P22748 3/20 0.36
CA6 P23280 3/20 0.36
CA5A P35218 3/20 0.36
CA7 P43166 3/20 0.36
CA9 Q16790 3/20 0.36
CA14 Q9ULX7 3/20 0.36
CA5B Q9Y2D0 3/20 0.36
TSHR P16473 2/20 0.36
F13A1 P00488 2/20 0.36
ALOX15 P16050 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121438 0.97 APP (0.48) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL12541657 0.95 APP (0.46) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL7108955 0.94 APP (0.50) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL917868 0.90 APP (0.42) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL918086 0.90 APP (0.42) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL918374 0.90 APP (0.42) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL791530 0.90 APP (0.61) APPCYP2C19LMNASLC6A6BLM
SCHEMBL28256664 0.89 APP (0.46) APPCYP2C19PTGS1PDE4ALMNA
SCHEMBL1898206 0.88 APP (0.65) APPCYP2C19LMNASLC6A6BLM
SCHEMBL917692 0.88 APP (0.41) APPCYP2C19PTGS1PDE4ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4003988-A1 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS Les Laboratoires Servier (FR) 2022-06-01 EP claimed
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-10-28 US claimed
WO-2021018857-A1 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS LES LABORATOIRES SERVIER (FR) 2021-02-04 WO claimed
EP-2747763-B1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RES & DEV (IL) 2020-12-30 EP claimed
CN-108976371-B High-performance sulfonic acid type waterborne polyurethane curing agent and preparation method and application thereof 华南理工大学 2020-10-27 CN claimed
US-20190231874-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RES & DEV (IL) 2019-08-01 US claimed
US-20160354468-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RES & DEV (IL) 2016-12-08 US claimed
US-20140378888-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) 2014-12-25 US claimed
EP-2747763-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS Yeda Research and Development Co. Ltd. (IL) 2014-07-02 EP claimed
US-8461142-B2 Water-soluble anionic bacteriochlorophyll derivatives and their uses YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-06-11 US claimed
WO-2013027222-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS YEDA RESEARCH AND DEVELOPMENT CO.LTD. (IL) 2013-02-28 WO claimed
EP-0626374-B1 A diaminostilbene series compound and a method for forming an image using the same FUJI PHOTO FILM CO LTD (JP) 2002-08-07 EP claimed
US-5395742-A IMAGEWISE EXPOSURE OF A PHOTOGRAPHIC MATERIAL TO LIGHT FUJI PHOTO FILM CO., LTD. (JP) 1995-03-07 US claimed
EP-0626374-A2 A diaminostilbene series compound and a method for forming an image using the same FUJI PHOTO FILM CO., LTD. (JP) 1994-11-30 EP claimed
US-5106990-A Absorb infrared radiation, discolor during photographic development FUJI PHOTO FILM CO., LTD. (JP) 1992-04-21 US claimed
WO-2023232829-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING ILLUMINA, INC (US) 2023-12-07 WO disclosed
US-20230383342-A1 COMPOSITIONS AND METHODS FOR NUCLEIC ACID SEQUENCING ILLUMINA, INC. 2023-11-30 US disclosed
US-4213153-A Process for the optical display of information using lasers Max-planck-Gesellschaft zur Fordenberg der Wissenschaften e.V. (DE) 1980-07-15 US disclosed
US-4206240-A Polymeric aminoanthrapyridine orange colors DYNAPOL (US) 1980-06-03 US disclosed
US-4196294-A Orange anthrapyridine monomeric colorants and colorant precursors DYNAPOL (US) 1980-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378888-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA APP 3395/4885CYP2C19 3091/4885PTGS1 1604/4885
US-20190231874-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA APP 3401/4885CYP2C19 3159/4885PTGS1 1825/4885
US-20160354468-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA APP 3401/4885CYP2C19 3159/4885PTGS1 1825/4885
US-20210330792-A1 (BACTERIO)CHLOROPHYLL PHOTOSENSITIZERS FOR TREATMENT OF EYE DISEASES AND DISORDERS PPOX, PPIB, PPIA APP 3401/4885CYP2C19 3159/4885PTGS1 1825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.