Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11212202 | 0.92 | MEN1 (0.38) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11216119 | 0.88 | KMT2A (0.37) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11217470 | 0.83 | ALDH1A1 (0.38) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11212205 | 0.80 | KMT2A (0.38) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11214162 | 0.79 | KMT2A (0.46) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL10332385 | 0.78 | ALDH1A1 (0.37) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11739896 | 0.77 | KMT2A (0.41) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11733493 | 0.77 | KMT2A (0.41) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11218592 | 0.75 | MEN1 (0.52) | LMNAMEN1KMT2AALDH1A1GAA | |
| SCHEMBL11732699 | 0.75 | MEN1 (0.41) | LMNAMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329454-A | Cephalosporin compounds | ELI LILLY AND COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |