Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11396877 | 0.86 | HSD17B10 (0.41) | GAASMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL18697298 | 0.82 | PPARG (0.47) | GAAALDH1A1MRGPRX4RXRARXRB | |
| SCHEMBL18697312 | 0.77 | TSHR (0.46) | GAASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL11225475 | 0.74 | HSD17B10 (0.61) | GAAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11239828 | 0.73 | LMNA (0.46) | GAASMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL11222790 | 0.71 | HSD17B1 (0.39) | KDM4EMEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL18697296 | 0.70 | MRGPRX4 (0.48) | KDM4EKMT2ANPSR1MRGPRX4RXRA | |
| SCHEMBL12310598 | 0.70 | AXL (0.47) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12473229 | 0.70 | AXL (0.47) | SMN1; SMN2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30116328 | 0.68 | PPARG (0.49) | GAAALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023584-B1 | PROCESS FOR THE PREPARATION OF TRIFLUOROMETHYL NAPHTHALENES | BAYER AG (DE) | 1983-01-26 | — | — | EP | disclosed |
| EP-0023584-A1 | Process for the preparation of trifluoromethyl naphthalenes | BAYER AG (DE) | 1981-02-11 | — | — | EP | disclosed |