Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15644535 | 0.81 | KMT2A (0.52) | PKMKMT2ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL6780237 | 0.80 | ALDH1A1 (0.46) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6100378 | 0.79 | SMN1; SMN2 (0.46) | KMT2ASMN1; SMN2FABP3FABP4MEN1 | |
| SCHEMBL3978692 | 0.79 | KMT2A (0.58) | KMT2AMAPTMEN1RECQLLMNA | |
| SCHEMBL11207364 | 0.75 | SMN1; SMN2 (0.65) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26239965 | 0.74 | LMNA (0.56) | PKMKMT2AHPGDSMN1; SMN2MAPT | |
| SCHEMBL8461947 | 0.73 | MAPT (0.54) | KMT2AFABP3FABP4MAPTNPC1 | |
| SCHEMBL4970400 | 0.72 | LMNA (0.48) | PKMKMT2AHPGDSMN1; SMN2LPAR1 | |
| SCHEMBL22897575 | 0.72 | SMN1; SMN2 (0.54) | PKMKMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL29559776 | 0.72 | SMN1; SMN2 (0.54) | PKMKMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034292-B1 | PROCESS FOR THE PREPARATION OF ANTHRANILIC ACID DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-11-23 | — | — | EP | disclosed |
| EP-0034292-A2 | Process for the preparation of anthranilic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1981-08-26 | — | — | EP | disclosed |