Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.37 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29120672 | 0.81 | ALOX5 (0.46) | ESR1ALOX15MEN1USP2LMNA | |
| SCHEMBL26884639 | 0.79 | ESR1 (0.63) | ESR1ESR2PTGDR2ALOX15LMNA | |
| SCHEMBL23735698 | 0.76 | CYP3A4 (0.46) | ESR1ESR2ALOX15MEN1LMNA | |
| SCHEMBL3959232 | 0.76 | NQO2 (0.55) | ESR1ESR2MEN1MAPTHPGD | |
| SCHEMBL9845623 | 0.75 | MPL (0.40) | LMNAHPGDHIF1APTGS1 | |
| SCHEMBL22275374 | 0.75 | NQO2 (0.54) | ESR1ESR2ALOX15MEN1SLC22A1 | |
| SCHEMBL18015817 | 0.74 | CYP2A6 (0.43) | MEN1KMT2AKCNH2FABP3FABP4 | |
| SCHEMBL21610041 | 0.73 | TSHR (0.40) | ESR1ESR2PTGDR2MEN1MAPT | |
| SCHEMBL30077833 | 0.72 | NQO2 (0.36) | ESR1ESR2ALOX15MEN1CYP3A4 | |
| SCHEMBL20315029 | 0.71 | GABRA1 (0.42) | ESR1ESR2MEN1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030701-B1 | PROCESS FOR THE MANUFACTURE OF 1-(ARALKYL)-2-NAPHTHOLS | BASF Aktiengesellschaft (DE) | 1983-04-20 | — | — | EP | disclosed |
| US-4320235-A | Preparation of 1-(aralkyl)-2-naphthols | BASF AKTIENGESELLSCHAFT (DE) | 1982-03-16 | — | — | US | disclosed |
| EP-0030701-A1 | Process for the manufacture of 1-(aralkyl)-2-naphthols | BASF Aktiengesellschaft (DE) | 1981-06-24 | — | — | EP | disclosed |