Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 12/20 | 0.51 |
| ▸ | PTAFR | P25105 | 9/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11210046 | 0.84 | ALPG (0.57) | ALPGTBXAS1PTAFR | |
| SCHEMBL11208277 | 0.84 | ALPG (0.74) | ALPGTBXAS1PTAFR | |
| SCHEMBL11219291 | 0.84 | TBXAS1 (0.43) | ALPGTBXAS1PTAFR | |
| SCHEMBL10767837 | 0.83 | AKR1B1 (0.55) | ALPGTBXAS1PTAFR | |
| SCHEMBL11203945 | 0.82 | ALPG (0.54) | ALPGTBXAS1PTAFR | |
| SCHEMBL11009207 | 0.82 | ALPG (0.67) | ALPGTBXAS1PTAFR | |
| SCHEMBL11270196 | 0.79 | PTAFR (0.55) | TBXAS1PTAFR | |
| SCHEMBL11008704 | 0.78 | PTAFR (0.54) | ALPGTBXAS1PTAFR | |
| SCHEMBL11005250 | 0.77 | ALPG (0.60) | ALPGTBXAS1PTAFR | |
| SCHEMBL11273433 | 0.76 | ALPG (0.68) | ALPGTBXAS1PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094080-A2 | Pyrido(2,1-b)quinazoline derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1983-11-16 | — | — | EP | disclosed |