Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209980 | 0.85 | MAPT (0.47) | NPC1MAPTHTTGAACA2 | |
| SCHEMBL11209332 | 0.83 | KMT2A (0.47) | NPC1RAB9AMAPTHTTKMT2A | |
| SCHEMBL11211507 | 0.83 | BCL2 (0.47) | MAPTHTTGAAKMT2AALDH1A1 | |
| SCHEMBL11213945 | 0.81 | MAPT (0.57) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11213117 | 0.81 | NPC1 (0.50) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11531709 | 0.80 | CA1 (0.58) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11291070 | 0.78 | NPC1 (0.48) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11208174 | 0.76 | NPC1 (0.54) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11287081 | 0.72 | NPC1 (0.50) | NPC1RAB9AMAPTHTTGAA | |
| SCHEMBL11294900 | 0.72 | MAPT (0.57) | NPC1RAB9AMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0079141-A1 | Aminoresorcinol derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1983-05-18 | — | — | EP | disclosed |