SCHEMBL11209332

SCHEMBL11209332

CC(C)(C)c1cc(C(=O)c2ccc(Cl)cc2)c(O)c(N)c1O

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
MEN1 O00255 1/20 0.47
RAB9A P51151 1/20 0.47
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
MAPK1 P28482 1/20 0.41
POLB P06746 2/20 0.40
NR4A1 P22736 1/20 0.40
ELANE P08246 1/20 0.39
NPC1 O15118 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
FABP2 P12104 1/20 0.38
PPARG P37231 1/20 0.38
PPARA Q07869 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11209980 0.87 MAPT (0.47) KMT2AMAPTMAPK1POLBNPC1
SCHEMBL11211507 0.85 BCL2 (0.47) KMT2AMEN1MAPTMAPK1POLB
SCHEMBL11216539 0.83 NPC1 (0.51) KMT2AMEN1RAB9AMAPTMAPK1
Hydrochloric Acid SCHEMBL11293225 0.83 RAB9A (0.47) KMT2AMEN1RAB9AMAPTTDP1
SCHEMBL4123639 0.82 GLRA3 (0.57) KMT2AMEN1RAB9AMAPTTDP1
SCHEMBL11209977 0.80 RAB9A (0.49) KMT2AMEN1RAB9AMAPTTDP1
Hydrochloric Acid SCHEMBL11208356 0.79 RAB9A (0.47) KMT2AMEN1RAB9AMAPTTDP1
SCHEMBL4113511 0.79 POLB (0.42) KMT2ARAB9AMAPTMAPK1POLB
SCHEMBL11213973 0.78 MAPT (0.48) KMT2AMEN1RAB9AMAPTTDP1
SCHEMBL11297259 0.77 POLB (0.45) KMT2AMEN1RAB9AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0079141-A1 Aminoresorcinol derivatives ONO PHARMACEUTICAL CO., LTD. (JP) 1983-05-18 EP disclosed