Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.72 |
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13696737 | 1.00 | LTA4H (0.72) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL2027392 | 0.85 | LTA4H (0.74) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL2032141 | 0.85 | LTA4H (0.74) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL5358938 | 0.85 | LTA4H (0.74) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL4701244 | 0.85 | LTA4H (0.74) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL7258949 | 0.84 | LTA4H (0.68) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL1893281 | 0.84 | LTA4H (1.00) | LTA4HMAOBLAP3MAOAGAA | |
| Hydrochloric Acid SCHEMBL4229807 | 0.84 | LTA4H (0.72) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL29399745 | 0.84 | LTA4H (1.00) | LTA4HMAOBLAP3MAOAGAA | |
| SCHEMBL1893279 | 0.84 | LTA4H (1.00) | LTA4HMAOBLAP3MAOAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329367-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |