SCHEMBL11216889

SCHEMBL11216889

CC(Oc1ccc(Cl)c(Cl)c1)C(=O)NCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.54
PPARA Q07869 1/20 0.54
MAPT P10636 3/20 0.54
ALDH1A1 P00352 3/20 0.54
PTGS2 P35354 1/20 0.53
HTT P42858 2/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
KDM4E B2RXH2 2/20 0.51
LMNA P02545 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
RECQL P46063 2/20 0.50
POLB P06746 1/20 0.50
KLKB1 P03952 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
TSHR P16473 2/20 0.48
ADAMTS5 Q9UNA0 1/20 0.47
CARM1 Q86X55 1/20 0.47
PRMT6 Q96LA8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10637956 0.85 PPARG (0.59) PPARGPPARAMAPTSMN1; SMN2KLKB1
SCHEMBL2610079 0.81 EPHX2 (0.60) MAPTALDH1A1HTTSMN1; SMN2KDM4E
SCHEMBL14643575 0.80 LMNA (0.78) PPARAMAPTALDH1A1PTGS2HTT
SCHEMBL11220675 0.78 ERCC1 (0.54) MAPTALDH1A1L3MBTL1KMT2A
SCHEMBL10053820 0.77 RECQL (0.62) ALDH1A1PTGS2HTTSMN1; SMN2KDM4E
SCHEMBL24439711 0.77 KDM4E (0.56) MAPTALDH1A1PTGS2HTTSMN1; SMN2
SCHEMBL28668952 0.76 KMT2A (0.68) ALDH1A1HTTL3MBTL1KMT2AMEN1
SCHEMBL14966284 0.75 KMT2A (0.62) MAPTALDH1A1PTGS2KDM4EL3MBTL1
SCHEMBL18791419 0.75 TSHR (0.68) ALDH1A1HTTSMN1; SMN2KDM4ELMNA
SCHEMBL10637909 0.75 SMN1; SMN2 (0.48) PPARGPPARAMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57014505-A None JP disclosed
JP-S5714505-A HERBICIDE UBE IND LTD 1982-01-25 JP disclosed