Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | RECQL | P46063 | 2/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605692 | 0.90 | MAPT (0.52) | KDM4ERECQLALDH1A1MAPTHPGD | |
| SCHEMBL24439709 | 0.90 | MAPT (0.52) | KDM4ERECQLALDH1A1MAPTHPGD | |
| SCHEMBL24439765 | 0.80 | HPGD (0.59) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29605285 | 0.80 | HPGD (0.59) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL24439852 | 0.78 | SMN1; SMN2 (0.53) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29605150 | 0.78 | SMN1; SMN2 (0.53) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL11216889 | 0.77 | PPARG (0.54) | KDM4ERECQLPTGS2ALDH1A1MAPT | |
| SCHEMBL29606995 | 0.75 | PTPN1 (0.54) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL24439766 | 0.73 | MEN1 (0.58) | KDM4EALDH1A1MAPTHPGDTSHR | |
| SCHEMBL29605252 | 0.73 | MEN1 (0.58) | KDM4EALDH1A1MAPTHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |