Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11214313 | 0.91 | SMN1; SMN2 (0.41) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11215371 | 0.85 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11398951 | 0.83 | ALDH1A1 (0.46) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11294057 | 0.82 | KMT2A (0.41) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11393669 | 0.82 | MAPT (0.40) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11361043 | 0.82 | ALDH1A1 (0.36) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11293028 | 0.81 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11296286 | 0.80 | NPC1 (0.42) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11356315 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL11293133 | 0.80 | ALDH1A1 (0.44) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314842-A | Herbicidal substituted 1,3,4-thiadiazol-2-yl-4-hydroxy-1-methyl-2-imidazolidinones | PPG INDUSTRIES, INC. (US) | 1982-02-09 | — | — | US | disclosed |