Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11232628 | 0.91 | LMNA (0.51) | SMN1; SMN2LMNAPDE4A | |
| Ioglucomide SCHEMBL668426 | 0.91 | SMN1; SMN2 (0.52) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11224662 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11523450 | 0.87 | SMN1; SMN2 (0.57) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11524954 | 0.86 | LMNA (0.46) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11526793 | 0.85 | LMNA (0.45) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11232347 | 0.84 | LMNA (0.44) | SMN1; SMN2LMNAPDE4A | |
| SCHEMBL11219689 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2LMNA | |
| SCHEMBL11218610 | 0.80 | LMNA (0.43) | SMN1; SMN2LMNA | |
| SCHEMBL11667001 | 0.79 | LMNA (0.40) | SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4314055-A | X-RAY CONTRAST AGENTS | MALLINCKRODT, INC. (US) | 1982-02-02 | — | — | US | disclosed |