Ioglucomide

Ioglucomide

SCHEMBL668426

CNC(=O)c1c(I)c(NC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c(I)c(NC(=O)[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)c1I

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.52
LMNA P02545 4/20 0.48
PDE4A P27815 1/20 0.37
KDM4E B2RXH2 2/20 0.33
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11232628 0.97 LMNA (0.51) SMN1; SMN2LMNAPDE4AKDM4ECYP2C19
SCHEMBL11224662 0.95 SMN1; SMN2 (0.60) SMN1; SMN2LMNAPDE4AKDM4ECYP2C19
SCHEMBL11523450 0.92 SMN1; SMN2 (0.57) SMN1; SMN2LMNAPDE4AKDM4ECYP2C19
SCHEMBL11524954 0.91 LMNA (0.46) SMN1; SMN2LMNAPDE4ACYP2C19HIF1A
SCHEMBL11217136 0.91 SMN1; SMN2 (0.45) SMN1; SMN2LMNAPDE4A
SCHEMBL11526793 0.90 LMNA (0.45) SMN1; SMN2LMNAPDE4ACYP2C19HIF1A
SCHEMBL11232347 0.89 LMNA (0.44) SMN1; SMN2LMNAPDE4ACYP2C19HIF1A
SCHEMBL11219689 0.86 SMN1; SMN2 (0.43) SMN1; SMN2LMNACYP2C19HIF1A
SCHEMBL11218610 0.85 LMNA (0.43) SMN1; SMN2LMNACYP2C19HIF1A
Ioglucol SCHEMBL3153740 0.84 CYP2C19 (0.42) SMN1; SMN2LMNACYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 270 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105120908-B The improved solidification of hardenable bone substitute 骨支撑股份公司 2018-04-27 CN claimed
CN-107660153-A Biphase ceramics bone substitute 骨支撑股份公司 2018-02-02 CN claimed
CN-105120908-A Improved setting of hardenable bone substitute BONE SUPPORT AB 2015-12-02 CN claimed
US-8268352-B2 Modified release composition for highly soluble drugs TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-18 US claimed
US-8263125-B2 Dosage form for high dose-high solubility active ingredients that provides for immediate release and modified release of the active ingredients TORRENT PHARMACEUTICALS LIMITED (IN) 2012-09-11 US claimed
CN-1878516-B Device for providing cancellous bone with bone substitute or bone reinforcing material BONE SUPPORT AB 2011-02-16 CN claimed
CN-1972648-B Device for producing a hardenable mass BONE SUPPORT AB 2011-02-09 CN claimed
CN-101790410-A From water soluble compound, remove silica by nanofiltration and RP chromatography MALLINCKRODT INC 2010-07-28 CN claimed
EP-1829565-B1 A new bone mineral substitute BONE SUPPORT AB (SE) 2010-02-17 EP claimed
CN-101107021-A Combinations comprising signal providing agents, implant materials and drugs CINV AG (DE) 2008-01-16 CN claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-0703790-B1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO SPA (IT) 2000-08-16 EP claimed
US-5660814-A Iodinated paramagnetic chelates, and their use as contrast agents DIBRA S.P.A. (IT) 1997-08-26 US claimed
EP-0703790-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.p.A. (IT) 1996-04-03 EP claimed
WO-1994027644-A1 IODINATED PARAMAGNETIC CHELATES, AND THEIR USE AS CONTRAST AGENTS BRACCO S.P.A. (IT) 1994-12-08 WO claimed
EP-0414288-B1 Contrast media NYCOMED IMAGING AS (NO) 1994-03-23 EP claimed
US-5242683-A Gastrointestinal tract, side effect reduction NYCOMED IMAGING AS (NO) 1993-09-07 US claimed
EP-0473729-A1 CONTRAST MEDIA NYCOMED AS (NO) 1992-03-11 EP claimed
EP-0414288-A1 Contrast media NYCOMED IMAGING AS (NO) 1991-02-27 EP claimed
WO-1991001149-A1 CONTRAST MEDIA NYCOMED AS (NO) 1991-02-07 WO claimed