Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668359 | 0.86 | HTT (0.53) | LMNACTSDHTTKDM4EALDH1A1 | |
| SCHEMBL669102 | 0.85 | GAA (0.53) | LMNASMN1; SMN2CTSDHTTKDM4E | |
| SCHEMBL14864224 | 0.84 | LMNA (0.53) | LMNASMN1; SMN2CTSDHTTKCNK3 | |
| SCHEMBL17950859 | 0.84 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2CTSDHTTKCNK3 | |
| SCHEMBL11199622 | 0.81 | MAPT (0.44) | LMNASMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL10139047 | 0.81 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2CTSDHTTKCNK3 | |
| SCHEMBL22560183 | 0.79 | LMNA (0.51) | LMNASMN1; SMN2CTSDHTTKCNK3 | |
| SCHEMBL9047582 | 0.78 | LMNA (0.50) | LMNASMN1; SMN2CTSDHTTKCNK3 | |
| SCHEMBL668052 | 0.77 | LMNA (0.49) | LMNASMN1; SMN2CTSDRAB9ANPC1 | |
| SCHEMBL10139031 | 0.77 | KDM4E (0.43) | LMNASMN1; SMN2KDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080419-A2 | 8-Haloalkyl-4H-(1)-benzopyran-4-ones and preparation processes | LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) | 1983-06-01 | — | — | EP | disclosed |