Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15344602 | 0.88 | PPARA (0.54) | LMNAHTTPPARAKDM4EALOX5 | |
| SCHEMBL9047582 | 0.86 | LMNA (0.50) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL3827916 | 0.86 | LMNA (0.52) | LMNASMN1; SMN2MAPTHTTPPARA | |
| SCHEMBL6617354 | 0.86 | PPARA (0.46) | LMNASMN1; SMN2HTTPPARAKDM4E | |
| Acetic Acid SCHEMBL27946451 | 0.85 | PPARA (0.54) | LMNAPPARAKDM4EALOX5PTGS2 | |
| SCHEMBL27787797 | 0.84 | CTSD (0.60) | SMN1; SMN2MAPTL3MBTL1PPARAKDM4E | |
| SCHEMBL17950859 | 0.83 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL10978263 | 0.83 | LTB4R (0.47) | LMNASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL5233773 | 0.82 | KCNK3 (0.57) | SMN1; SMN2MAPTKDM4EALDH1A1MAPK1 | |
| SCHEMBL11245246 | 0.82 | PPARA (0.62) | HTTPPARAKDM4EALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | BAYLOR UNIVERSITY (US) | 2020-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10807932-B2 | Benzosuberene analogues and related compounds with activity as anticancer agents | TUBB1, TUBB3, TUBB | LMNA 927/4885SMN1; SMN2 2568/4885MAPT 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.