SCHEMBL11217540

SCHEMBL11217540

C=COC(C)=O.CCCCOC(=O)C1=C(C(=O)O)CC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
TSHR P16473 8/20 0.41
HPGD P15428 2/20 0.41
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CHRM2 P08172 4/20 0.37
CHRM4 P08173 4/20 0.37
CHRM5 P08912 4/20 0.37
CHRM1 P11229 4/20 0.37
CHRM3 P20309 4/20 0.37
ESR1 P03372 5/20 0.36
MAPK1 P28482 3/20 0.36
LMNA P02545 2/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2D6 P10635 1/20 0.36
NR1H2 P55055 1/20 0.36
RNASEL Q05823 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ATM Q13315 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4449462 0.85 TSHR (0.49) ALDH1A1TSHRTDP1L3MBTL1CHRM2
SCHEMBL10602593 0.81
SCHEMBL9863146 0.79 TSHR (0.46) ALDH1A1TSHRTDP1L3MBTL1CHRM2
SCHEMBL11564363 0.79 TSHR (0.55) ALDH1A1TSHRHPGDTDP1L3MBTL1
SCHEMBL4912283 0.78 ALDH1A1 (0.41) ALDH1A1TSHRHPGDTDP1L3MBTL1
SCHEMBL17728019 0.78 SCD (0.35) ALDH1A1TSHRCHRM2CHRM4CHRM5
SCHEMBL28238053 0.78 ALDH1A1 (0.53) ALDH1A1TSHRHPGDTDP1L3MBTL1
Acetic Acid Butyl Ester SCHEMBL17797769 0.77 ALDH1A1 (0.69) ALDH1A1TSHRHPGDTDP1L3MBTL1
SCHEMBL5819431 0.77 TSHR (0.51) ALDH1A1TSHRHPGDTDP1L3MBTL1
SCHEMBL5607518 0.76 LMNA (0.48) ALDH1A1TSHRHPGDTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4363836-A WATERPROOF ADHESIVE SHIN-ETSU CHEMICAL CO., LTD. (JP) 1982-12-14 US disclosed