Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 17/20 | 0.35 |
| ▸ | SLC6A2 known ✓ | P23975 | 13/20 | 0.35 |
| ▸ | SLC6A4 known ✓ | P31645 | 9/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23733432 | 0.98 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL23866055 | 0.98 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL3300015 | 0.98 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4HRH3 | |
| Ammonia Solution, Strong SCHEMBL464958 | 0.95 | SLC6A3 (0.35) | SLC6A3SLC6A2SLC6A4HRH3 | |
| Iodide SCHEMBL10559193 | 0.95 | SLC6A3 (0.35) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL2229569 | 0.95 | SLC6A3 (0.37) | SLC6A3SLC6A2SLC6A4 | |
| Iodide SCHEMBL15008320 | 0.93 | SLC6A3 (0.36) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3302667 | 0.88 | SLC6A3 (0.38) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL28067947 | 0.86 | HRH3 (0.33) | SLC6A3SLC6A2SLC6A4HRH3 | |
| SCHEMBL898138 | 0.85 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013904-B1 | PROCESS FOR THE PREPARATION OF POLYCARBONATES | BAYER AG (DE) | 1983-03-09 | — | — | EP | disclosed |