SCHEMBL898138

SCHEMBL898138

CCCC(CCC)N1CCCC1

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 17/20 0.39
SLC6A2 P23975 14/20 0.39
SLC6A4 P31645 10/20 0.38
HRH3 Q9Y5N1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL15008876 0.97 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL3302667 0.97 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL22701318 0.94 SLC6A3 (0.35) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL14160126 0.91 HRH3 (0.40) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL2229569 0.90 SLC6A3 (0.37) SLC6A3SLC6A2SLC6A4
SCHEMBL24869964 0.89 HRH3 (0.42) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL14204509 0.89 HRH3 (0.42) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL21164045 0.89 HRH3 (0.42) SLC6A3SLC6A2SLC6A4HRH3
SCHEMBL8494598 0.89 SLC6A3 (0.38) SLC6A3SLC6A2SLC6A4
SCHEMBL18403963 0.89 SLC6A3 (0.34) SLC6A3SLC6A2SLC6A4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230295096-A1 PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV ASSEMBLY BIOSCIENCES INC (US) 2023-09-21 US disclosed
CN-116635228-A Surface protective film 日东电工株式会社 2023-08-22 CN disclosed
EP-4194548-A1 GENERATION OF HUMAN PLURIPOTENT STEM CELL DERIVED FUNCTIONAL BETA CELLS SHOWING A GLUCOSE-DEPENDENT MITOCHONDRIAL RESPIRATION AND TWO-PHASE INSULIN SECRETION RESPONSE Janssen Biotech, Inc. (US) 2023-06-14 EP disclosed
US-11413682-B2 Method for producing surface-modified metal oxide fine particle, method for producing improved metal oxide fine particles, surface-modified metal oxide fine particles, and metal oxide fine particle dispersion liquid TOKYO OHKA KOGYO CO., LTD. (JP) 2022-08-16 US disclosed
EP-3998339-A1 EXON SKIPPING COMPOSITIONS FOR TREATING MUSCULAR DYSTROPHY Sarepta Therapeutics, Inc. (US) 2022-05-18 EP disclosed
US-20200139433-A1 METHOD FOR PRODUCING SURFACE-MODIFIED METAL OXIDE FINE PARTICLE, METHOD FOR PRODUCING IMPROVED METAL OXIDE FINE PARTICLES, SURFACE-MODIFIED METAL OXIDE FINE PARTICLES, AND METAL OXIDE FINE PARTICLE DISPERSION LIQUID TOKYO OHKA KOGYO CO., LTD. (JP) 2020-05-07 US disclosed
CN-110476003-A Heat-insulated insulation substrate NITTO DENKO CORP 2019-11-19 CN disclosed
CN-107074890-B Alkenyl (perfluoroalkyl) phosphinic acids 默克专利股份公司 2019-09-24 CN disclosed
CN-104342049-B Bonding sheet and optical component 日东电工株式会社 2019-07-23 CN disclosed
CN-104342050-B Bonding sheet and optical component 日东电工株式会社 2019-06-07 CN disclosed
US-7838533-B2 Azaindole inhibitors of MTP and ApoB MERCK PATENT GMBH (DE) 2010-11-23 US disclosed
EP-1628957-B1 SULFOPYRROLES TAKEDA PHARMACEUTICAL (JP) 2010-09-29 EP disclosed
US-20100099031-A1 NONAQUEOUS ELECTROLYTES AND NONAQUEOUS-ELECTROLYTE SECONDARY BATTERIES EMPLOYING THE SAME MITSUBISHI CHEMICAL CORPORATION (JP) 2010-04-22 US disclosed
EP-2166611-A1 NONAQUEOUS ELECTROLYTE, AND RECHARGEABLE BATTERY WITH THE NONAQUEOUS ELECTROLYTE Mitsubishi Chemical Corporation (JP) 2010-03-24 EP disclosed
US-7612064-B2 Sulfopyrroles TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-03 US disclosed
US-7612064-B2 Sulfopyrroles TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2009-11-03 US disclosed
US-20090036481-A1 Novel Azaindole Inhibitors of Mtp and Apob MERCK PATENT GMBH (DE) 2009-02-05 US disclosed
EP-1467974-B1 BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS GNRH ANTAGONISTS SOD CONSEILS RECH APPLIC (FR) 2007-08-15 EP disclosed
US-20070060570-A1 Sulfopyrroles TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-15 US disclosed
US-20070060570-A1 Sulfopyrroles TALEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2007-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036481-A1 Novel Azaindole Inhibitors of Mtp and Apob APOB, MTPN, HDLBP SLC6A3 3398/4885SLC6A2 2532/4885SLC6A4 2305/4885
US-20230295096-A1 PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV HCCS, HAVCR2, MAVS SLC6A3 4869/4885SLC6A2 4874/4885SLC6A4 4804/4885
US-20070060570-A1 Sulfopyrroles TYK2, ARSA, SULT2A1 SLC6A3 3486/4885SLC6A2 4023/4885SLC6A4 4060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.