Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.41 |
| ▸ | BRSK1 | Q8TDC3 | 1/20 | 0.41 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10781878 | 0.82 | NISCH (0.49) | NOTUMNPY5RPARP1PIM1GSK3B | |
| SCHEMBL10899939 | 0.78 | PGR (0.42) | NOTUMPARP10PARP11 | |
| SCHEMBL4361638 | 0.76 | AXL (0.52) | XDHMAPT | |
| SCHEMBL22309155 | 0.76 | PDE3B (0.47) | — | |
| SCHEMBL22308851 | 0.76 | PDE3B (0.54) | NOTUMMAPT | |
| SCHEMBL11625391 | 0.75 | SMN1; SMN2 (0.59) | NOTUMPARP10PARP11XDHPDCD1 | |
| SCHEMBL22308343 | 0.75 | PDE3B (0.39) | — | |
| SCHEMBL22308344 | 0.75 | PDE3B (0.41) | — | |
| SCHEMBL4691651 | 0.73 | MAOB (0.51) | NOTUM | |
| SCHEMBL22309145 | 0.73 | PDE3B (0.42) | NOTUMIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362550-A | Herbicidal triazinones | ELI LILLY AND COMPANY (US) | 1982-12-07 | — | — | US | claimed |
| US-4362550-A | Herbicidal triazinones | ELI LILLY AND COMPANY (US) | 1982-12-07 | — | — | US | disclosed |