SCHEMBL11218560

SCHEMBL11218560

NC(=O)c1cccc(C(N)=O)c1C(N)=O.Nc1ccccc1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 3/20 0.50
KDM4E B2RXH2 2/20 0.50
MAPT P10636 2/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
METAP2 P50579 1/20 0.47
GAA P10253 2/20 0.46
MMP2 P08253 1/20 0.45
BCAT2 O15382 1/20 0.45
IKBKB O14920 2/20 0.44
KEAP1 Q14145 1/20 0.44
NFE2L2 Q16236 1/20 0.44
CFTR P13569 1/20 0.44
CYP3A4 P08684 1/20 0.43
ALOX15 P16050 1/20 0.43
CASP1 P29466 1/20 0.43
CASP7 P55210 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CTNNB1 P35222 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1512043 0.89 MMP2 (0.47) ALDH1A1HSD17B10KDM4EMAPTHPGD
SCHEMBL466296 0.89 KDM4E (0.54) ALDH1A1HSD17B10KDM4EMAPTHPGD
SCHEMBL28907979 0.86 ALDH1A1 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
SCHEMBL6066755 0.82 KDM4E (0.48) ALDH1A1HSD17B10KDM4EMAPTHPGD
Anthranilamide SCHEMBL2801971 0.81 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
Anthranilamide SCHEMBL7650571 0.81 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
Anthranilamide SCHEMBL38228 0.81 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
Anthranilamide SCHEMBL7655669 0.81 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
Anthranilamide SCHEMBL29391044 0.81 HSD17B10 (0.58) ALDH1A1HSD17B10KDM4EMAPTHPGD
SCHEMBL5807527 0.80 MAPT (0.63) ALDH1A1HSD17B10KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0015149-B1 INTERFACIALLY SYNTHESIZED REVERSE OSMOSIS MEMBRANE, PROCESS FOR THE PREPARATION THEREOF AND ITS USE IN A PROCESS FOR REMOVING SOLUTE FROM SOLUTE-CONTAINING WATER FilmTec Corporation (US) 1983-06-22 EP disclosed
US-4277344-A CROSSLINKED AROMATIC POLYAMIDE FILM ON MICROPOROUS SUPPORT FILMTEC CORPORATION (US) 1981-07-07 US disclosed
EP-0015149-A1 Interfacially synthesized reverse osmosis membrane, process for the preparation thereof and its use in a process for removing solute from solute-containing water FilmTec Corporation (US) 1980-09-03 EP disclosed