Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11159363 | 0.81 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL18169216 | 0.78 | TP53 (0.65) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL25969107 | 0.77 | KDM4E (0.69) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL3843267 | 0.75 | MEN1 (0.60) | MEN1KMT2ATP53KDM4EHSD17B10 | |
| SCHEMBL23297235 | 0.72 | MEN1 (0.72) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL23479895 | 0.72 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL11393727 | 0.72 | HSD17B10 (0.50) | PDE4APDE4BPDE4CPDE4DMEN1 | |
| SCHEMBL23297349 | 0.72 | MEN1 (0.72) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL23297247 | 0.71 | MEN1 (0.70) | MEN1KMT2ATP53KDM4EALDH1A1 | |
| SCHEMBL11158417 | 0.71 | KDM4E (0.52) | MEN1KMT2ATP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57188574-A | — | — | None | — | — | JP | disclosed |
| JP-S57188574-A | PYRIDAZINONE DERIVATIVE | MORISHITA SEIYAKU KK | 1982-11-19 | — | — | JP | disclosed |