Sugi Predict

Sugi Predict / Compounds / SCHEMBL112190

SCHEMBL112190

SCHEMBL112190

Cc1cc(C2=NOC(c3cc(Cl)cc(Cl)c3)(C(F)(F)F)C2)ccc1C(=O)NCc1ccccn1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HPGD P15428 5/20 0.46
▸ RAB9A P51151 3/20 0.46
▸ KDM4E B2RXH2 4/20 0.44
▸ SORT1 Q99523 1/20 0.42
▸ LMNA P02545 6/20 0.42
▸ ALDH1A1 P00352 5/20 0.42
▸ SMN1; SMN2 Q16637 4/20 0.42
▸ HTT P42858 3/20 0.42
▸ MAPT P10636 2/20 0.42
▸ KMT2A Q03164 2/20 0.41
▸ MEN1 O00255 1/20 0.41
▸ L3MBTL1 Q9Y468 2/20 0.41
▸ NPC1 O15118 3/20 0.40
▸ CYP1A2 P05177 2/20 0.40
▸ CYP3A4 P08684 1/20 0.40
▸ CYP2C19 P33261 1/20 0.40
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2353716 0.96 HPGD (0.43) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL15999816 0.94 HPGD (0.45) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL16106146 0.91 HPGD (0.44) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL740350 0.91 HPGD (0.46) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL740089 0.91 HPGD (0.44) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL738531 0.91 HPGD (0.44) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL737522 0.91 HPGD (0.45) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL740727 0.91 HPGD (0.45) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL737917 0.90 LMNA (0.48) HPGDRAB9AKDM4ESORT1LMNA
SCHEMBL677678 0.89 LMNA (0.49) HPGDRAB9AKDM4ESORT1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 371 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3646731-A1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-05-06 — — EP claimed
EP-3300602-B1 PESTICIDAL MIXTURES COMPRISING A PYRAZOLE COMPOUND BASF SE (DE) 2020-03-25 — — EP claimed
EP-3351243-A1 ANIMAL PEST CONTROL METHOD E. I. du Pont de Nemours and Company (US) 2018-07-25 — — EP claimed
EP-2957284-B1 ANIMAL PEST CONTROL METHOD DU PONT (US) 2018-01-17 — — EP claimed
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION 2016-08-04 — — US claimed
US-9339030-B2 Foamable pesticide compositions and methods of application BASF CORPORATION (US) 2016-05-17 — — US claimed
EP-2182945-B1 ANIMAL PEST CONTROL METHOD DU PONT (US) 2015-08-05 — — EP claimed
US-20150105258-A1 Methods For Controlling Pests BASF CORPORATION (US) 2015-04-16 — — US claimed
US-8980294-B2 Methods for controlling pests BASF CORPORATION (US) 2015-03-17 — — US claimed
US-8940662-B2 Methods for controlling pests BASF CORPORATION (US) 2015-01-27 — — US claimed
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application BASF CORPORATION (US) 2012-06-14 — — US claimed
EP-2424370-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF Corporation (US) 2012-03-07 — — EP claimed
EP-2424347-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF Corporation (US) 2012-03-07 — — EP claimed
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds BASF SE (DE) 2011-09-15 — — US claimed
WO-2011025789-A2 FOAMABLE PESTICIDE COMPOSITIONS AND METHODS OF APPLICATION BASF CORPORATION (US) 2011-03-03 — — WO claimed
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-12-23 — — US claimed
US-20100322990-A1 METHODS FOR CONTROLLING PESTS BASF CORPORATION (US) 2010-12-23 — — US claimed
WO-2010129345-A2 FOAMABLE PESTICIDE COMPOSITIONS BASF CORPORATION (US) 2010-11-11 — — WO claimed
WO-2010127019-A1 PESTICIDE COMPOSITIONS AND APPLICATORS BASF CORPORATION (US) 2010-11-04 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120149570-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE HPGD 1593/4885RAB9A 674/4885KDM4E 4540/4885
US-20100323897-A1 FOAMABLE PESTICIDE COMPOSITIONS DDT, PON1, ACHE HPGD 2223/4885RAB9A 1110/4885KDM4E 2927/4885
US-20110224075-A1 Pesticidal Active Mixtures Comprising Aminothiazoline Compounds CBR3, AOC3, MT-CO3 HPGD 4019/4885RAB9A 2260/4885KDM4E 4003/4885
US-20100322990-A1 METHODS FOR CONTROLLING PESTS DDT, ACHE, PON1 HPGD 3929/4885RAB9A 557/4885KDM4E 1971/4885
US-20100322892-A1 PESTICIDE COMPOSITIONS AND APPLICATORS DDT, ACHE, CHRM2 HPGD 4241/4885RAB9A 2225/4885KDM4E 3406/4885
US-20150105258-A1 Methods For Controlling Pests DDT, ACHE, PON1 HPGD 3929/4885RAB9A 557/4885KDM4E 1971/4885
US-20160219872-A1 Foamable Pesticide Compositions And Methods Of Application DDT, PLD1, ACHE HPGD 1593/4885RAB9A 674/4885KDM4E 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.