SCHEMBL11219010

SCHEMBL11219010

Fc1ccc2ccccc2c1Nc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 5/20 0.50
ALDH1A1 P00352 5/20 0.50
KDM1A O60341 5/20 0.50
TSHR P16473 3/20 0.50
HPGD P15428 3/20 0.50
CYP3A4 P08684 2/20 0.50
ALOX15 P16050 2/20 0.50
CDC25B P30305 2/20 0.50
TP53 P04637 1/20 0.50
ATM Q13315 1/20 0.50
HPRT1 P00492 2/20 0.41
TDP1 Q9NUW8 3/20 0.41
CYP2A6 P11509 1/20 0.41
KDM4E B2RXH2 2/20 0.41
MAPT P10636 2/20 0.41
RECQL P46063 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
GLA P06280 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17022824 0.78 ALDH1A1 (0.62) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL820048 0.77 ALDH1A1 (0.50) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL626743 0.77 HSD17B10 (0.50) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL28165939 0.77 KDM1A (0.50) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL28503835 0.77 HSD17B10 (0.50) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL10871261 0.77 G6PD (0.54) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL22125088 0.76 CYP2A6 (0.44) HSD17B10ALDH1A1TSHRHPRT1TDP1
SCHEMBL4979017 0.76 HSD17B10 (0.48) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL20336265 0.76 HSD17B10 (0.48) HSD17B10ALDH1A1KDM1ATSHRHPGD
SCHEMBL20702679 0.75 HSD17B10 (0.48) HSD17B10ALDH1A1KDM1ATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170321075-A1 PHOTOCURABLE INK COMPOSITION, RECORDING METHOD, RECORDING APPARATUS, PHOTOCURABLE INK JET RECORDING INK COMPOSITION, AND INK JET RECORDING METHOD SEIKO EPSON CORPORATION (JP) 2017-11-09 US disclosed
US-20170190806-A1 FUNCTIONALISED NITRILE RUBBERS AND THE PRODUCTION THEREOF LANXESS DEUTSCHLAND GMBH (DE) 2017-07-06 US disclosed
EP-2991813-A1 VACUUM PRE-CASTING OF POLYAMIDE POLYMERS Invista Technologies S.A R.L. (CH) 2016-03-09 EP disclosed
US-9052631-B2 Image forming apparatus, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2015-06-09 US disclosed
WO-2014179056-A1 VACUUM PRE-CASTING OF POLYAMIDE POLYMERS INVISTA TECHNOLOGIES S.À.R.L. (CH) 2014-11-06 WO disclosed
US-20140178103-A1 IMAGE FORMING APPARATUS, PROCESS CARTRIDGE, AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2014-06-26 US disclosed
EP-0083786-A2 Vulcanizable epoxide-containing ethylene copolymers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-07-20 EP disclosed