SCHEMBL11219451

SCHEMBL11219451

c1ccc2c(c1)ccc1sc(SSc3nc4c(ccc5ccccc54)s3)nc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 4/20 0.48
TDP1 Q9NUW8 3/20 0.48
FBP1 P09467 3/20 0.48
ALOX15 P16050 2/20 0.48
HPGD P15428 2/20 0.48
ADRA2A P08913 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
DRD2 P14416 1/20 0.48
ADRA2B P18089 1/20 0.48
ADRA2C P18825 1/20 0.48
DRD1 P21728 1/20 0.48
MC5R P33032 1/20 0.48
OPRM1 P35372 1/20 0.48
DRD3 P35462 1/20 0.48
OPRK1 P41145 1/20 0.48
CCR2 P41597 1/20 0.48
HTR6 P50406 1/20 0.48
SLC6A3 Q01959 1/20 0.48
PDK1 Q15118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30602945 0.86 TDP1 (0.45) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL9300879 0.86 TDP1 (0.45) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL11590047 0.78 XIAP (0.40) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL1801464 0.77 ALDH1A1 (0.52) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL7905015 0.76 ALDH1A1 (0.46) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL22457218 0.76 XIAP (0.48) ALDH1A1HSD17B10TDP1ALOX15HPGD
Bromide SCHEMBL4961408 0.76 ALDH1A1 (0.50) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL2170681 0.76 RAB9A (0.53) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL29843187 0.76 RAB9A (0.53) ALDH1A1HSD17B10TDP1ALOX15HPGD
SCHEMBL2211087 0.76 XIAP (0.44) ALDH1A1HSD17B10TDP1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4138346-A ETHOXYLATED PHOSPHATE ESTER WITH A MERCAPTOTHIAZOLE, A DITHIOBIS-THIAZOLE, A SULFIDE, A DISULFIDE OR A SULFONE BASF WYANDOTTE CORPORATION (US) 1979-02-06 US claimed
US-3933658-A PHOSPHATE ESTER AND SULFUR COMPOUND GAF CORPORATION (US) 1976-01-20 US claimed
US-4343660-A PETROLEUM SULFONATE AND COMPLEXING AGENT, FOR COPPER CABLES PETROLITE CORPORATION (US) 1982-08-10 US disclosed