Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GALR3 | O60755 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218527 | 0.87 | MAPT (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL4228872 | 0.81 | KDM4E (0.61) | ALDH1A1GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL2913722 | 0.80 | ALDH1A1 (0.57) | ALDH1A1GAAKDM4ESMN1; SMN2TLR8 | |
| SCHEMBL11219578 | 0.77 | CNR1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL6605124 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL11151420 | 0.72 | HCRTR1 (0.77) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL6608984 | 0.72 | HTT (0.58) | ALDH1A1SMN1; SMN2MAPTHTTMEN1 | |
| SCHEMBL15563826 | 0.71 | ALDH1A1 (0.52) | ALDH1A1GAAKDM4ESMN1; SMN2MAPT | |
| SCHEMBL18641090 | 0.71 | ALDH1A1 (0.65) | ALDH1A1GAAKDM4EMAPTHSD17B10 | |
| SCHEMBL11226584 | 0.71 | RXFP1 (0.49) | ALDH1A1KDM4ESMN1; SMN2MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0089597-A2 | Sulphonyl ureas, process for their preparation, pharmaceutical compositions containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-09-28 | — | — | EP | disclosed |