Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11218527 | 0.81 | MAPT (0.47) | SMN1; SMN2ALDH1A1MAPTHSD17B10PKM | |
| SCHEMBL6601700 | 0.81 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL15563826 | 0.79 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1MAPTPPARDPPARA | |
| SCHEMBL6608984 | 0.79 | HTT (0.58) | SMN1; SMN2ALDH1A1MAPTGLAHPGD | |
| SCHEMBL15945346 | 0.78 | SMN1; SMN2 (0.50) | SMN1; SMN2MAPTHSD17B10PPARDPPARA | |
| SCHEMBL15563981 | 0.78 | PPARD (0.46) | SMN1; SMN2ALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL15563505 | 0.77 | MAPT (0.50) | SMN1; SMN2MAPTHSD17B10PPARDPPARA | |
| SCHEMBL6603045 | 0.75 | KDM4E (0.51) | SMN1; SMN2ALDH1A1MAPTHPGDPPARD | |
| SCHEMBL15945345 | 0.75 | MAPT (0.55) | SMN1; SMN2ALDH1A1MAPTHSD17B10HPGD | |
| SCHEMBL11219489 | 0.74 | ALDH1A1 (0.51) | SMN1; SMN2ALDH1A1MAPTHSD17B10RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412349-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | Schering Aktiengesellschaft (DE) | 2004-04-28 | — | — | EP | claimed |
| WO-2002098856-A2 | PIPERAZINE OXYQUINOLINE (NAPHTHALINE) PLATELET ADENOSINE DIPHOSPHATE RECEPTOR ANTAGONISTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2002-12-12 | — | — | WO | claimed |