Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10576000 | 0.81 | GSK3B (0.52) | GSK3BHSD17B10P2RY6GRIN1GRIN2A | |
| SCHEMBL13664653 | 0.81 | HSD17B10 (0.47) | ALDH1A1HSD17B10P2RY6GRIN1GRIN2A | |
| SCHEMBL3322047 | 0.79 | HSD17B10 (0.47) | ALDH1A1TRPA1HSD17B10P2RY6GRIN1 | |
| SCHEMBL941258 | 0.78 | P2RY6 (0.50) | ALDH1A1HSD17B10P2RY6GRIN1GRIN2A | |
| SCHEMBL13496887 | 0.77 | HSD17B10 (0.44) | ALDH1A1MAPK1HSD17B10P2RY6GRIN1 | |
| SCHEMBL11480265 | 0.77 | GSK3B (0.80) | GSK3BALDH1A1HIF1ATRPA1MAPK1 | |
| SCHEMBL23481284 | 0.76 | HSD17B10 (0.49) | ALDH1A1TRPA1HSD17B10P2RY6GRIN1 | |
| SCHEMBL455561 | 0.76 | MIF (0.54) | ALDH1A1TRPA1HSD17B10P2RY6TP53 | |
| SCHEMBL9313240 | 0.75 | PLOD2 (0.58) | GSK3BALDH1A1MAPK1HSD17B10P2RY6 | |
| SCHEMBL10576522 | 0.75 | P2RY6 (0.52) | ALDH1A1TRPA1HSD17B10P2RY6GRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4328311-A | USEFUL IN IMMUNOASSAY | SYVA COMPANY (US) | 1982-05-04 | — | — | US | disclosed |
| US-4220722-A | ACYLATION, AMIDATION, SULFIDING | SYVA COMPANY (US) | 1980-09-02 | — | — | US | disclosed |