SCHEMBL455561

SCHEMBL455561

O=C(O)c1ccc(N=C=S)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.54
HSD17B10 Q99714 1/20 0.53
TSHR P16473 3/20 0.52
TP53 P04637 1/20 0.52
TRPA1 O75762 1/20 0.52
CA2 P00918 7/20 0.50
CA1 P00915 6/20 0.50
CA12 O43570 2/20 0.50
CA9 Q16790 2/20 0.50
P2RY6 Q15077 1/20 0.48
SRD5A2 P31213 1/20 0.46
CA3 P07451 1/20 0.44
TYR P14679 1/20 0.44
DRD1 P21728 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27517752 0.98 MIF (0.52) MIFHSD17B10TSHRTP53TRPA1
Paraben SCHEMBL6755103 0.92 CA2 (0.59) MIFHSD17B10TSHRTP53TRPA1
SCHEMBL6755096 0.86 PRSS1 (0.53) HSD17B10
SCHEMBL941258 0.84 P2RY6 (0.50) MIFHSD17B10CA2CA1P2RY6
SCHEMBL23481284 0.83 HSD17B10 (0.49) MIFHSD17B10TRPA1CA2CA1
SCHEMBL635606 0.82 MIF (0.59) MIFHSD17B10TRPA1CA2CA1
SCHEMBL3398682 0.81 KDM4E (0.50) MIFHSD17B10TRPA1CA2CA1
SCHEMBL1308638 0.81 NOS3 (0.53) MIFHSD17B10CA2CA1P2RY6
SCHEMBL10576522 0.81 P2RY6 (0.52) MIFHSD17B10TSHRTRPA1CA2
SCHEMBL3322047 0.81 HSD17B10 (0.47) MIFHSD17B10TRPA1CA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115818810-B Composite polyaluminium chloride water treatment agent and preparation method thereof 安徽科凌沃特水处理技术有限公司 2024-12-27 CN claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117457312-A Magnetic molecular probe for specifically capturing metabolites from complex sample, and preparation method and application thereof 中国医学科学院基础医学研究所 2024-01-26 CN claimed
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 CN claimed
CN-114853650-B Material for specifically capturing ammonia compounds from complex sample and preparation method and application thereof 中国医学科学院基础医学研究所 2023-04-28 CN claimed
CN-115818810-A Composite polyaluminium chloride water treatment agent and preparation method thereof 安徽科凌沃特水处理技术有限公司 2023-03-21 CN claimed
CN-114853650-A Material for specifically capturing ammonia compound from complex sample and preparation method and application thereof 中国医学科学院基础医学研究所 2022-08-05 CN claimed
US-20220233501-A1 THERAPEUTIC COMBINATIONS SUPERSALUS INC (US) 2022-07-28 US claimed
CN-110681495-B Thiourea compound flotation separation inhibitor and flotation separation method thereof 北京矿冶科技集团有限公司 2021-08-06 CN claimed
WO-2020167748-A1 THERAPEUTIC COMBINATIONS SUPERSALUS, INC. (US) 2020-08-20 WO claimed
US-20200253926-A1 THERAPEUTIC COMBINATIONS SUPERSALUS, INC. 2020-08-13 US claimed
CN-110681495-A Thiourea compound flotation separation inhibitor and flotation separation method thereof 北京矿冶科技集团有限公司 2020-01-14 CN claimed
EP-2445345-B1 BENZAMIDE DERIVATIVES TRANSLATIONAL GENOMICS RES INST (US) 2014-08-27 EP claimed
US-20120125775-A1 CHEMICAL MODIFICATION OF PROTEINS FOR THEIR MORE ACCURATE MOLECULAR-WEIGHT DETERMINATION BY ELECTROPHORESIS DOLNIK VLADISLAV (US) 2012-05-24 US claimed
US-20070190659-A1 Method for analyzing n-terminal protein adducts ADDUCT ANALYS AB (SE) 2007-08-16 US claimed
EP-1738177-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS Adduct Analys AB (SE) 2007-01-03 EP claimed
WO-2005101020-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS ADDUCT ANALYS AB (SE) 2005-10-27 WO claimed
EP-0236646-B1 ORTHO-ANISAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL APPLICATIONS Laboratoires DELAGRANGE, Société Anonyme (FR) 1990-10-10 EP claimed
EP-0236646-A1 Ortho-anisamides, process for their preparation and their pharmaceutical applications Laboratoires DELAGRANGE, Société Anonyme (FR) 1987-09-16 EP claimed
EP-4701635-A1 1,2,4-TRIAZOLE-3-THIONE INHIBITORS OF TREX2 FOR USE IN THE TREATMENT OF PSORIASIS, ATOPIC DERMATITIS OR ICHTHYOSIS Universitat De Barcelona (ES) 2026-03-04 EP disclosed
EP-4508038-A1 COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO The United States Government as represented by the Department of Veterans Affairs (US) 2025-02-19 EP disclosed
CN-115818810-B Composite polyaluminium chloride water treatment agent and preparation method thereof 安徽科凌沃特水处理技术有限公司 2024-12-27 CN disclosed
WO-2024223907-A1 1,2,4-TRIAZOLE-3-THIONE INHIBITORS OF TREX2 FOR USE IN THE TREATMENT OF PSORIASIS, ATOPIC DERMATITIS OR ICHTHYOSIS UNIVERSITAT DE BARCELONA (ES) 2024-10-31 WO disclosed
CN-115557908-B Triazine derivative containing sulfur connecting bond, and synthesis method and application thereof 九江学院 2024-10-15 CN disclosed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN disclosed
CN-117457312-A Magnetic molecular probe for specifically capturing metabolites from complex sample, and preparation method and application thereof 中国医学科学院基础医学研究所 2024-01-26 CN disclosed
CN-117342991-A Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof 华新水泥股份有限公司 2024-01-05 CN disclosed
WO-2023201374-A1 COMPOSITIONS AND METHODS FOR INHIBITING CARP-1 BINDING TO NEMO THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2023-10-19 WO disclosed
CN-116761484-A Perovskite film and preparation method and application thereof 青岛科技大学 2023-09-15 CN disclosed
CN-113402473-B Thiotriazole compound, preparation method and application thereof 四川省医学科学院·四川省人民医院 2023-06-23 CN disclosed
CN-114853650-B Material for specifically capturing ammonia compounds from complex sample and preparation method and application thereof 中国医学科学院基础医学研究所 2023-04-28 CN disclosed
CN-115818810-A Composite polyaluminium chloride water treatment agent and preparation method thereof 安徽科凌沃特水处理技术有限公司 2023-03-21 CN disclosed
CN-115557908-A Triazine derivative containing sulfur connecting bond and synthesis method and application thereof 九江学院 2023-01-03 CN disclosed
CN-114853650-A Material for specifically capturing ammonia compound from complex sample and preparation method and application thereof 中国医学科学院基础医学研究所 2022-08-05 CN disclosed
US-20220233501-A1 THERAPEUTIC COMBINATIONS SUPERSALUS INC (US) 2022-07-28 US disclosed
CN-111849122-B Resin composition and application thereof 常熟生益科技有限公司 2022-06-14 CN disclosed
US-20220031661-A1 SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION UNIVERSITY OF KANSAS 2022-02-03 US disclosed
CN-113402473-A Thiotriazole compound, preparation method and application thereof 四川省医学科学院·四川省人民医院 2021-09-17 CN disclosed
CN-110681495-B Thiourea compound flotation separation inhibitor and flotation separation method thereof 北京矿冶科技集团有限公司 2021-08-06 CN disclosed
CN-111849122-A Resin composition and application thereof 常熟生益科技有限公司 2020-10-30 CN disclosed
WO-2020167748-A1 THERAPEUTIC COMBINATIONS SUPERSALUS, INC. (US) 2020-08-20 WO disclosed
US-20200253926-A1 THERAPEUTIC COMBINATIONS SUPERSALUS, INC. 2020-08-13 US disclosed
CN-106916101-B NAMPT/HDAC double-target inhibitor and preparation method thereof 聚缘(上海)生物科技有限公司 2020-05-01 CN disclosed
CN-110681495-A Thiourea compound flotation separation inhibitor and flotation separation method thereof 北京矿冶科技集团有限公司 2020-01-14 CN disclosed
US-9486535-B2 Methods of making and using nanostructures TYCHON BIOSCIENCE, LLC (US) 2016-11-08 US disclosed
US-9486535-B2 Methods of making and using nanostructures TYCHON BIOSCIENCE, LLC (US) 2016-11-08 US disclosed
US-RE46171-E1 Functional biopolymer modification reagents and uses thereof SOLULINK, INCORPORATED (US) 2016-10-04 US disclosed
US-RE46171-E1 Functional biopolymer modification reagents and uses thereof SOLULINK, INCORPORATED (US) 2016-10-04 US disclosed
EP-2492262-B1 FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL IND LTD (JP) 2016-04-20 EP disclosed
US-9102602-B2 Method for producing isothiocyanate compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-11 US disclosed
US-9102602-B2 Method for producing isothiocyanate compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-11 US disclosed
US-9102602-B2 Method for producing isothiocyanate compound NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2015-08-11 US disclosed
US-8889732-B2 Fused heterocyclic compounds and thrombopoietin receptor activators NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-11-18 US disclosed
US-20140249191-A1 Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases AVIENNE PHARMACEUTICALS GMBH (AT) 2014-09-04 US disclosed
EP-1660519-B1 Conjugates comprising 2-[18F]fluoro-2-deoxy-D-glucose and a peptide molecule IMMUNOMEDICS INC (US) 2014-05-14 EP disclosed
CN-101965331-B Method for producing isothiocyanate compound having carboxyl group NISSAN CHEMICAL IND LTD 2014-04-16 CN disclosed
US-8614330-B2 Substituted benz-azoles and methods of their use as inhibitors of RAF kinase NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2013-12-24 US disclosed
EP-2647623-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2013-10-09 EP disclosed
EP-2647623-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND Nissan Chemical Industries, Ltd. (JP) 2013-10-09 EP disclosed
US-20130245305-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-20130245305-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-20130245305-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-09-19 US disclosed
US-8497371-B2 Pipemidic acid derivative autotaxin inhibitors UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2013-07-30 US disclosed
US-8449880-B2 Chemical modification of proteins for their more accurate molecular-weight determination by electrophoresis DOLNIK VLADISLAV (US) 2013-05-28 US disclosed
US-8367857-B2 Method for producing isothiocyanate compound having carboxyl group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-02-05 US disclosed
EP-2240175-B1 COMPOUNDS WITH MDR1-INVERSE ACTIVITY US GOV HEALTH & HUMAN SERV (US) 2013-01-02 EP disclosed
US-20120288501-A1 SUBSTITUTED BENZAZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE NOVARTIS VACCINES AND DIAGNOSTICS, INC. FORMERLY KNOWN AS CHIRON CORPORATION (US) 2012-11-15 US disclosed
US-8299108-B2 for treatment of hematological/hormone-dependent cancer NOVARTIS AG (CH) 2012-10-30 US disclosed
EP-2492262-A1 FUSED HETEROCYCLIC COMPOUND AND THROMBOPOIETIN RECEPTOR ACTIVATOR Nissan Chemical Industries, Ltd. (JP) 2012-08-29 EP disclosed
US-20120209005-A1 FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-08-16 US disclosed
US-20120125775-A1 CHEMICAL MODIFICATION OF PROTEINS FOR THEIR MORE ACCURATE MOLECULAR-WEIGHT DETERMINATION BY ELECTROPHORESIS DOLNIK VLADISLAV (US) 2012-05-24 US disclosed
US-20120100592-A1 PIPEMIDIC ACID DERIVATIVE AUTOTAXIN INHIBITORS THE UNIVERSITY OF MEMPHIS 2012-04-26 US disclosed
WO-2012033601-A1 THIOSEMICARBAZONES WITH MDR1 - INVERSE ACTIVITY THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) 2012-03-15 WO disclosed
US-8053453-B2 Pyrazolone compounds and thrombopoietin receptor activator NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2011-11-08 US disclosed
WO-2011053597-A1 PIPEMIDIC ACID DERIVATIVE AUTOTAXIN INHIBITORS THE UNIVERSITY OF MEMPHIS RESEARCH FOUNDATION (US) 2011-05-05 WO disclosed
CN-101965331-A Method for producing isothiocyanate compound having carboxyl group NISSAN CHEMICAL IND LTD 2011-02-02 CN disclosed
US-20100316655-A1 COMPOUNDS WITH MDR1-INVERSE ACTIVITY INSTITUTE OF ENZYMOLOGY, BIOLOGICAL RESEARCH CENTER, HUNGARIAN ACADEMY OF SCIENCES (HU) 2010-12-16 US disclosed
US-20100312000-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2010-12-09 US disclosed
EP-2248800-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP Nissan Chemical Industries, Ltd. (JP) 2010-11-10 EP disclosed
EP-2240175-A2 COMPOUNDS WITH MDR1-INVERSE ACTIVITY The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services (US) 2010-10-20 EP disclosed
US-20100196368-A1 SUBSTITUTED BENZ-AZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2010-08-05 US disclosed
US-7732628-B2 Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis SOLULINK INCORPORATED (US) 2010-06-08 US disclosed
US-7732628-B2 Such as 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]benzaldehyde, 4-[8-(2-cyanoethyl-N,N-diisopropylphosphoramidyloxy)-2-aza-1-oxooct-1-yl]acetophenone; for incorporation into oligonucleotides during immobilization and conjugation of biopolymers in solid phase synthesis SOLULINK INCORPORATED (US) 2010-06-08 US disclosed
US-7728010-B2 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase NOVARTIS VACCINES AND DIAGNOSTICS, INC. (US) 2010-06-01 US disclosed
US-7718437-B2 Method for analyzing N-terminal protein adducts ADDUCT ANALYS AB (SE) 2010-05-18 US disclosed
US-7662977-B2 PI-3 kinase inhibitor prodrugs SEMAFORE PHARMACEUTICALS, INC. (US) 2010-02-16 US disclosed
US-7652047-B2 Phenylamino isothiazole carboxamidines as MEK inhibitors ARDEA BIOSCIENCES, INC. (US) 2010-01-26 US disclosed
EP-1499311-B1 SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS NOVARTIS VACCINES & DIAGNOSTIC (US) 2009-11-04 EP disclosed
WO-2009102433-A2 COMPOUNDS WITH MDR1-INVERSE ACTIVITY THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2009-08-20 WO disclosed
US-7572459-B2 Prevention infections in humans, animals STARPHARMA PTY LTD. (AU) 2009-08-11 US disclosed
US-7566549-B2 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2009-07-28 US disclosed
CN-100515419-C Substituted benzazoles and its application as inhibitors of Raf kinase CHIRON CORP (US) 2009-07-22 CN disclosed
EP-1738177-B1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS ADDUCT ANALYS AB (SE) 2009-02-11 EP disclosed
CN-101352451-A Anionic or cationic dendrimer antimicrobial or antiparasitic compositions STARPHARMA PTY LTD (AU) 2009-01-28 CN disclosed
US-20090011975-A1 TARGETED BONE MARROW PROTECTION AGENTS SEMAFORE PHARMACEUTICALS INC. (US) 2009-01-08 US disclosed
US-20080306063-A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS ARDEA BIOSCIENCES, INC. (US) 2008-12-11 US disclosed
US-7429667-B2 Phenylamino isothiazole carboxamidines as MEK inhibitors ARDEA BIOSCIENCES, INC. (US) 2008-09-30 US disclosed
US-20080188423-A1 PI-3 KINASE INHIBITOR PRODRUGS SIGNALRX PHARMACEUTICALS, INC. 2008-08-07 US disclosed
US-7396828-B2 PI-3 kinase inhibitor prodrugs SEMAFORE PHARMACEUTICALS, INC. (US) 2008-07-08 US disclosed
WO-2008061029-A1 ARYL SULFONAMIDE DERIVATIVES AND METHODS OF THEIR USE WYETH (US) 2008-05-22 WO disclosed
US-20070299039-A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase CHIRON CORPORATION (US) 2007-12-27 US disclosed
EP-1113806-B1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA PTY LTD (AU) 2007-09-05 EP disclosed
US-20070190659-A1 Method for analyzing n-terminal protein adducts ADDUCT ANALYS AB (SE) 2007-08-16 US disclosed
US-20070122859-A1 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD GHOSHAL MITALI 2007-05-31 US disclosed
CN-1913884-A Substituted benzazoles and methods of their use as inhibitors of RAF kinase CHIRON CORP (US) 2007-02-14 CN disclosed
EP-1738177-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS Adduct Analys AB (SE) 2007-01-03 EP disclosed
US-7157560-B2 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2007-01-02 US disclosed
WO-2006133417-A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS VALEANT PHARMACEUTICALS INTERNATIONAL (US) 2006-12-14 WO disclosed
US-7144989-B2 Pegylated non-hypertensive hemoglobins, methods of preparing same, and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2006-12-05 US disclosed
US-7102024-B1 Functional biopolymer modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2006-09-05 US disclosed
US-20060194802-A1 Phenylamino isothiazole carboxamidines as MEK inhibitors ARDEA BIOSCIENCES, INC. 2006-08-31 US disclosed
US-7084112-B2 Activated polyethylene glycol compounds ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2006-08-01 US disclosed
EP-1675584-A1 SUBSTITUTED BENZAZOLES AND USE THEREOF AS INHIBITORS OF RAF KINASE CHIRON CORPORATION (US) 2006-07-05 EP disclosed
US-7071216-B2 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase CHIRON CORPORATION (US) 2006-07-04 US disclosed
EP-0927217-B1 ANGIOGENIC INHIBITORY COMPOUNDS STARPHARMA PTY LTD (AU) 2006-05-03 EP disclosed
US-20060069140-A1 Pyrazolone compounds and thrombopoietin receptor activator NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-03-30 US disclosed
EP-1615639-A2 TARGETED BONE MARROW PROTECTION AGENTS Semafore Pharmaceuticals, Inc. (US) 2006-01-18 EP disclosed
EP-1611119-A1 PI-3 KINASE INHIBITOR PRODRUGS Semafore Pharmaceuticals, Inc. (US) 2006-01-04 EP disclosed
US-6962954-B2 Activated polyethylene glycol compounds ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2005-11-08 US disclosed
WO-2005101020-A1 METHOD FOR ANALYZING N-TERMINAL PROTEIN ADDUCTS ADDUCT ANALYS AB (SE) 2005-10-27 WO disclosed
US-6949537-B2 PI-3 kinase inhibitor prodrugs SEMAFORE PHARMACEUTICALS, INC. (US) 2005-09-27 US disclosed
US-20050203289-A1 Functional biopolymer modification reagents and uses thereof AUDAX PRIVATE DEBT LLC, AS AGENT 2005-09-15 US disclosed
US-20050203173-A1 PI-3 kinase inhibitor prodrugs SIGNALRX PHARMACEUTICALS, INC. 2005-09-15 US disclosed
CN-1655779-A substituted indoles and their use as Raf kinase inhibitors CHIRON CORP (US) 2005-08-17 CN disclosed
US-20050159339-A1 Pegylated non-hypertensive hemoglobins, methods of preparing same, and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. 2005-07-21 US disclosed
CN-1638770-A Composition and potentiating method NEW PHARMA RES SWEDEN AB (SE) 2005-07-13 CN disclosed
EP-1549618-A1 PYRAZOLONE COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS Nissan Chemical Industries, Ltd. (JP) 2005-07-06 EP disclosed
WO-2005032548-A1 SUBSTITUTED BENZAZOLES AND USE THEREOF AS INHIBITORS OF RAF KINASE CHIRON CORPORATION (US) 2005-04-14 WO disclosed
US-6858739-B2 Indole and benzimidazole 15-lipoxygenase inhibitors WARNER-LAMBERT COMPANY (US) 2005-02-22 US disclosed
EP-1499311-A1 SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS Chiron Corporation (US) 2005-01-26 EP disclosed
US-20040242631-A1 PI-3 kinase inhibitor prodrugs SIGNALRX PHARMACEUTICALS, INC. 2004-12-02 US disclosed
EP-1042276-B1 THIOUREA COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS WARNER LAMBERT CO (US) 2004-11-17 EP disclosed
WO-2004089925-A1 PI-3 KINASE INHIBITOR PRODRUGS SEMAFORE PHARMACEUTICALS, INC. (US) 2004-10-21 WO disclosed
WO-2004089356-A2 TARGETED BONE MARROW PROTECTION AGENTS SEMAFORE PHARMACEUTICALS INC. (US) 2004-10-21 WO disclosed
US-20040198783-A1 Targeted bone marrow protection agents SEMAFORE PHARMACEUTICALS INC. 2004-10-07 US disclosed
US-6794496-B2 2-OXO-DERIVATIVES OF LSD; HAPTEN DERIVATIVES USED TO PREPARE ANTIGENS, ANTIBODIES AND REAGENTS FOR USE IN IMMUNOASSAYS. ROCHE DIAGNOSTICS CORPORATION 2004-09-21 US disclosed
CN-1161128-C Angiogenic inhibitory compounds О 2004-08-11 CN disclosed
US-20040147736-A1 Activated polyethylene glycol compounds ALBERT EINSTEIN COLLEGE OF MEDICINE, INC. 2004-07-29 US disclosed
US-20040127697-A1 Activated polyethylene glycol compounds ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY 2004-07-01 US disclosed
US-20040122237-A1 Substituted benzazoles and methods of their use as inhibitors of Raf kinase NOVARTIS AG (CH) 2004-06-24 US disclosed
EP-1113805-A4 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LTD (AU) 2004-05-19 EP disclosed
US-6737524-B2 ARYL ISOTHIOCYANATE DERIVATIVES; ATTACHING TO BIOMOLECULES SUCH AS PROTEINS OR PEPTIDES; ENHANCING IN VIVO CIRCULATION HALFLIFE Smith, Paul K. 2004-05-18 US disclosed
US-20040087626-A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase NOVARTIS AG (CH) 2004-05-06 US disclosed
WO-2004033433-A1 PYRAZOLONE COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATOR NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2004-04-22 WO disclosed
US-6720345-B1 NON PEPTIDES; TREATMENT OF THROMBOCYTOPENIA AND OTHER CONDITIONS WITH DEPRESSED PLATELET FORMATION; PROMOTERS OF THROMBOPOIESIS AND MEGAKARYOCYTOPOIESIS; BLOOD GROWTH FACTOR AGONIST ABLE TO ACCELERATE PLATELET REGENERATION. SMITHKLINE BEECHAM CORPORATION 2004-04-13 US disclosed
US-20040038943-A1 Indole and benzimidazole 15-lipoxygenase inhibitors CONNOR DAVID THOMAS (US) 2004-02-26 US disclosed
EP-0816364-B1 Reagents for lysergic acid diethylamide immunoassay HOFFMANN LA ROCHE (CH) 2004-01-02 EP disclosed
WO-2003082272-A1 SUBSTITUTED BENZAZOLES AND USE THEREOF AS RAF KINASE INHIBITORS CHIRON CORPORATION (US) 2003-10-09 WO disclosed
US-20030187248-A1 Activated polyethylene glycol compounds ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY 2003-10-02 US disclosed
US-20030129158-A1 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions STARPHARMA LIMITED 2003-07-10 US disclosed
EP-1113806-A4 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA LTD (AU) 2003-06-25 EP disclosed
EP-0927217-A4 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RES INST LTD (AU) 2003-04-23 EP disclosed
EP-1294686-A2 INDOLE DERIVATIVES AND THEIR USE AS 15-LIPOXYGENASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2003-03-26 EP disclosed
US-6528528-B2 Inhibitors of 15-lipoxygenase, inhibiting chemotaxis of monocytes WARNER-LAMBERT COMPANY 2003-03-04 US disclosed
US-20030013131-A1 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD ROCHE DIAGNOSTICS OPERATIONS, INC. 2003-01-16 US disclosed
US-6476199-B1 Reagents for lysergic acid diethylamide immunoassay ROCHE DIAGNOSTICS CORPORATION 2002-11-05 US disclosed
US-6464971-B1 ANIONIC-CONTAINING MOIETY IS A NEURAMINIC- OR SIALIC ACID-CONTAINING. MOIETY, IT IS MODIFIED IN THE 4-POSITION BY SUBSTITUTION WITH AN AMINO, AMIDO, CYANO, AZIDO OR GUANIDO GROUP, OR IS UNSATURATED. STARPHARMA LIMITED (AU) 2002-10-15 US disclosed
EP-1228051-A1 SEMICARBAZONE DERIVATIVES AND THEIR USE AS THROMBOPOIETIN MIMETICS SmithKline Beecham Corporation (US) 2002-08-07 EP disclosed
US-6426067-B1 CARDIOVASCULAR DISORDERS; ANTITUMOR AGENTS BIOMOLECULAR RESEARCH INSTITUTE, LTD. (AU) 2002-07-30 US disclosed
WO-2002010431-A2 FUNCTIONAL BIOPOLYMER MODIFICATION REAGENTS AND USES THEREOF SCHWARTZ DAVID A (US) 2002-02-07 WO disclosed
WO-2001096299-A2 INDOLE DERIVATIVES AND THEIR USE AS 15-LIPOXYGENASE INHIBITORS WARNER-LAMBERT COMPANY (US) 2001-12-20 WO disclosed
US-20010044118-A1 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD ROCHE DIAGNOSTICS OPERATIONS, INC. 2001-11-22 US disclosed
CN-1323214-A Antimicrobial or antiparasitic compositions of anionic or cationic dendrimers STARPHARMA LTD (AU) 2001-11-21 CN disclosed
CN-1323215-A Inhibition of toxic materials or substances using dendrimers STARPHARMA LTD (AU) 2001-11-21 CN disclosed
EP-1148339-A2 Immunoassay for LSD and 2-Oxo-3-Hydroxy-LSD Roche Diagnostics Corporation (US) 2001-10-24 EP disclosed
US-20010031874-A1 Thiourea and benzamide compounds, compositions and methods of treating or preventing inflammatory diseases and atherosclerosis CONNOR DAVID THOMAS (US) 2001-10-18 US disclosed
US-6268387-B1 INHIBITORS OF THE ENZYME 15-LIPOXYGENASE AND ARE INHIBITORS OF MONOCYTE CHEMOTAXIS. WARNER-LAMBERT COMPANY 2001-07-31 US disclosed
EP-1113805-A1 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS Starpharma Limited (AU) 2001-07-11 EP disclosed
EP-1113806-A1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS Starpharma Limited (AU) 2001-07-11 EP disclosed
WO-2001034585-A1 SEMICARBAZONE DERIVATIVES AND THEIR USE AS THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 2001-05-17 WO disclosed
US-6217845-B1 IMAGING; THERAPY ANORMED, INC. (CA) 2001-04-17 US disclosed
EP-1042276-A1 THIOUREA COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY LLC (US) 2000-10-11 EP disclosed
US-6063908-A STABLE HAPTEN DERIVATIVES THAT ARE USEFUL FOR THE PREPARATION OF ANTIGENS, ANTIBODIES AND REAGENTS USED IN DETECTION OF DRUG ABUSE ROCHE DIAGNOSTICS CORPORATION (US) 2000-05-16 US disclosed
WO-2000015240-A1 ANIONIC OR CATIONIC DENDRIMER ANTIMICROBIAL OR ANTIPARASITIC COMPOSITIONS STARPHARMA LIMITED (AU) 2000-03-23 WO disclosed
WO-2000015239-A1 INHIBITION OF TOXIC MATERIALS OR SUBSTANCES USING DENDRIMERS STARPHARMA LIMITED (AU) 2000-03-23 WO disclosed
CN-1225654-A Angiogenic inhibitory compounds BIOMOLECULAR RES INST LTD (AU) 1999-08-11 CN disclosed
EP-0927217-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1999-07-07 EP disclosed
WO-1999032433-A1 THIOUREA AND BENZAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS WARNER-LAMBERT COMPANY (US) 1999-07-01 WO disclosed
EP-0664825-B1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS SECR DEFENCE BRIT (GB) 1999-03-31 EP disclosed
US-5753520-A BIOCHEMICAL CONJUGATED WITH A HYDRAZINE OR A HYDRAZONE COMPOUND AS DRUG DELIVERY; HIGH BIOLOGICAL SPECIFICITY; MEDICINE FOR IMAGING, THERAPY, RADIOACTIVE TAGGING JOHNSON MATTHEY INC. (US) 1998-05-19 US disclosed
WO-1998003573-A1 ANGIOGENIC INHIBITORY COMPOUNDS BIOMOLECULAR RESEARCH INSTITUTE LTD. (AU) 1998-01-29 WO disclosed
EP-0816364-A1 Reagents for lysergic acid diethylamide immunoassay F. HOFFMANN-LA ROCHE AG (CH) 1998-01-07 EP disclosed
US-5578242-A LIQUID CRYSTALS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE RESEARCH AGENCY (GB) 1996-11-26 US disclosed
EP-0384769-B1 Protein labelling JOHNSON MATTHEY PLC (GB) 1996-04-24 EP disclosed
EP-0664825-A1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND (GB) 1995-08-02 EP disclosed
US-5420285-A Imaging for medicine JOHNSON MATTHEY, INC. (US) 1995-05-30 US disclosed
US-5393883-A Ribonucleotide reductase inhibitors BURROUGHS WELLCOME CO. (US) 1995-02-28 US disclosed
WO-1994009085-A1 THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF THE DEFENCE RESEARCH AGENCY (GB) 1994-04-28 WO disclosed
US-5206370-A Certain pyridyl hydrazines and hydrazides useful for protein labeling JOHNSON MATTHEY, INC. (US) 1993-04-27 US disclosed
US-5175165-A Acyclovir and a thiocarbonohydrazone ribonucleotide reductase inhibitor for treatment of herpes virus BURROUGHS WELLCOME CO. (US) 1992-12-29 US disclosed
EP-0349243-B1 ANTIVIRAL COMBINATIONS AND COMPOUNDS THEREFOR THE WELLCOME FOUNDATION LIMITED (GB) 1992-04-01 EP disclosed
EP-0220899-B1 BIFUNCTIONAL LINKER Immunomedics, Inc. (US) 1992-03-11 EP disclosed
EP-0384769-A2 Protein labelling JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 1990-08-29 EP disclosed
US-4914117-A ANTIDEPRESSANTS, CENTRAL NERVOUS SYSTEM ACTIVATORS; DOPAMINE ANTAGONISTS SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE-D-FRANCE (FR) 1990-04-03 US disclosed
EP-0349243-A2 Antiviral combinations and compounds therefor THE WELLCOME FOUNDATION LIMITED (GB) 1990-01-03 EP disclosed
EP-0117511-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-09-20 EP disclosed
US-4835172-A Novel benzamides, intermediates and process for the preparation and therapeutic use thereof SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) 1989-05-30 US disclosed
US-4824659-A LINKED TO POLY(AMIDE,UREA,THIOUREA); BORON CAGE COMPOUNDS; RADIOTHERAPY OF TUMORS IMMUNOMEDICS, INC. (US) 1989-04-25 US disclosed
US-4680338-A Bifunctional linker IMMUNOMEDICS, INC. (US) 1987-07-14 US disclosed
EP-0220899-A1 Bifunctional linker Immunomedics, Inc. (US) 1987-05-06 EP disclosed
US-4628024-A RELEASING A FOGGING AGENT; CONTRAST; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-12-09 US disclosed
EP-0117511-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-09-05 EP disclosed
EP-0117511-A2 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1984-09-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (27 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040122237-A1 Substituted benzazoles and methods of their use as inhibitors of Raf kinase BRAF, RAF1, ARAF MIF 3961/4885HSD17B10 2741/4885TSHR 3584/4885
US-20030187248-A1 Activated polyethylene glycol compounds ADH1C, PIGO, AADAC MIF 980/4885HSD17B10 1780/4885TSHR 2255/4885
US-20090011975-A1 TARGETED BONE MARROW PROTECTION AGENTS APAF1, BST2, MCL1 MIF 57/4885HSD17B10 4392/4885TSHR 4135/4885
US-20040087626-A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase BRAF, RAF1, ARAF MIF 3921/4885HSD17B10 2353/4885TSHR 3487/4885
US-20050203289-A1 Functional biopolymer modification reagents and uses thereof OGG1, OGA, HMOX2 MIF 3934/4885HSD17B10 1839/4885TSHR 2148/4885
US-20120209005-A1 FUSED HETEROCYCLIC COMPOUNDS AND THROMBOPOIETIN RECEPTOR ACTIVATORS MPL, TEK, THPO MIF 1456/4885HSD17B10 4111/4885TSHR 53/4885
US-20040198783-A1 Targeted bone marrow protection agents APAF1, BST2, MCL1 MIF 57/4885HSD17B10 4392/4885TSHR 4135/4885
US-20040038943-A1 Indole and benzimidazole 15-lipoxygenase inhibitors ALOX15, ALOX5, ALOX12 MIF 1133/4885HSD17B10 100/4885TSHR 2040/4885
US-20010044118-A1 Immunoassay for LSD and 2-oxo-3-hydroxy-LSD HNMT, HRH3, HRH4 MIF 771/4885HSD17B10 1739/4885TSHR 2601/4885
US-20080306063-A1 PHENYLAMINO ISOTHIAZOLE CARBOXAMIDINES AS MEK INHIBITORS BRAF, MAP4K2, MAP3K4 MIF 701/4885HSD17B10 4101/4885TSHR 2919/4885
US-20010031874-A1 Thiourea and benzamide compounds, compositions and methods of treating or preventing inflammatory diseases and atherosclerosis TPMT, CTH, CBS MIF 504/4885HSD17B10 2178/4885TSHR 901/4885
US-20120288501-A1 SUBSTITUTED BENZAZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE BRAF, RAF1, ARAF MIF 3961/4885HSD17B10 2741/4885TSHR 3584/4885
US-20120100592-A1 PIPEMIDIC ACID DERIVATIVE AUTOTAXIN INHIBITORS ENPP2, PLA2G6, PLA2G10 MIF 2324/4885HSD17B10 2224/4885TSHR 3334/4885
US-20100196368-A1 SUBSTITUTED BENZ-AZOLES AND METHODS OF THEIR USE AS INHIBITORS OF RAF KINASE BRAF, RAF1, ARAF MIF 3921/4885HSD17B10 2353/4885TSHR 3487/4885
US-20100312000-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP CBS, CTH, TST MIF 4284/4885HSD17B10 1193/4885TSHR 2373/4885
US-20060194802-A1 Phenylamino isothiazole carboxamidines as MEK inhibitors BRAF, MAP4K2, MAP3K4 MIF 701/4885HSD17B10 4101/4885TSHR 2919/4885
US-20140249191-A1 Compositions for Controlling Vascularization in Ophthalmological and Dermatological Diseases FLT1, KDR, FLT4 MIF 1619/4885HSD17B10 277/4885TSHR 4075/4885
US-20070299039-A1 Substituted benz-azoles and methods of their use as inhibitors of Raf kinase BRAF, RAF1, ARAF MIF 3921/4885HSD17B10 2353/4885TSHR 3487/4885
US-20050203173-A1 PI-3 kinase inhibitor prodrugs PI4KA, PI4KB, PI4K2B MIF 1708/4885HSD17B10 3277/4885TSHR 3974/4885
US-20080188423-A1 PI-3 KINASE INHIBITOR PRODRUGS PI4KA, PI4KB, PI4K2B MIF 1708/4885HSD17B10 3277/4885TSHR 3974/4885
US-20040242631-A1 PI-3 kinase inhibitor prodrugs PI4KA, PI4KB, PI4K2B MIF 1708/4885HSD17B10 3277/4885TSHR 3974/4885
US-20030129158-A1 Anionic or cationic dendrimer antimicrobial or antiparasitic compositions FUT6, B3GNT2, SIGLEC7 MIF 680/4885HSD17B10 4464/4885TSHR 2560/4885
US-20040127697-A1 Activated polyethylene glycol compounds ADH1C, PIGO, AADAC MIF 980/4885HSD17B10 1780/4885TSHR 2255/4885
US-20100316655-A1 COMPOUNDS WITH MDR1-INVERSE ACTIVITY ABCC1, ABCB1, ABCC2 MIF 482/4885HSD17B10 2666/4885TSHR 4378/4885
US-20220031661-A1 SMALL MOLECULE INHIBITORS OF THE BFRB:BFD INTERACTION BLVRB, TFPI, ETFB MIF 2072/4885HSD17B10 553/4885TSHR 1599/4885
US-20060069140-A1 Pyrazolone compounds and thrombopoietin receptor activator MPL, PDGFRA, THPO MIF 2149/4885HSD17B10 2907/4885TSHR 174/4885
US-20130245305-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND TST, CTH, ICMT MIF 2087/4885HSD17B10 2778/4885TSHR 2627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.