Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11219615 | 0.84 | MAOB (0.53) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL335459 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL5395245 | 0.78 | RAB9A (0.53) | RAB9ASMN1; SMN2KMT2ANPC1MAPT | |
| SCHEMBL354105 | 0.78 | NR4A2 (1.00) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL9518714 | 0.78 | MEN1 (0.59) | ALDH1A1CYP2C19RAB9ASMN1; SMN2CYP1A2 | |
| Hydrazine SCHEMBL3522472 | 0.76 | RAB9A (0.51) | RAB9ASMN1; SMN2KMT2ANPC1MAPT | |
| SCHEMBL7408024 | 0.76 | NR4A2 (0.95) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| Hydrochloric Acid SCHEMBL1372562 | 0.76 | NR4A2 (0.95) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL6604571 | 0.76 | NR4A2 (0.95) | NR4A2ALDH1A1GAACYP2C19LMNA | |
| SCHEMBL6547078 | 0.76 | NR4A2 (0.95) | NR4A2ALDH1A1GAACYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161421-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | Pharmacia & Upjohn Aktiebolag (SE) | 2001-12-12 | — | — | EP | disclosed |
| WO-2000053583-A1 | INHIBITORS OF PROTEIN TYROSINE PHOSPHATASE | BIOVITRUM AB (SE) | 2000-09-14 | — | — | WO | disclosed |