Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PON1 | P27169 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599041 | 0.73 | KDM4E (0.60) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL27921849 | 0.69 | RAPGEF4 (0.45) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL4884877 | 0.69 | CYP1A2 (0.50) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL317299 | 0.67 | RAPGEF4 (0.50) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL1551822 | 0.67 | RAPGEF4 (0.59) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL28951 | 0.67 | RAPGEF4 (0.59) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL38659759 | 0.67 | ELANE (0.41) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL10412763 | 0.65 | RAPGEF4 (0.56) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL5180888 | 0.65 | RAPGEF4 (0.56) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL28482658 | 0.65 | RAPGEF4 (0.56) | RAPGEF4KDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4339595-A | Hexa(meta-,para-carboxyphenyl)benzene compounds | STANDARD OIL COMPANY (INDIANA) (US) | 1982-07-13 | — | — | US | disclosed |